Results 91 to 100 of about 4,602 (229)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Fractional strong metric dimension of convex polytopes and its applications
Hacettepe Journal of Mathematics and StatisticsThe fractional versions of various metric related parameters have recently gained importance due to their applications in the fields of sensor networking, robot navigation and linear optimization problems. Convex polytopes are collection of those polytopes of Euclidean space which are their convex subsets.
Faiza Jamil, Agha Kashif, Sohail Zafar
openaire +2 more sources
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
The fractional Liouville equation in dimension 1 Geometry, Compactness and quantization (Analysis on Shapes of Solutions to Partial Differential Equations) [PDF]
, 2018 We discuss some recent results about the fractional Liouville equation in dimension 1 and related questions. These results, resting on a geometric interpretation in terms of holomorphic maps, on the study of geodesics in a conformal metric and on a ...
Riviere, Tristan +2 more
core
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
On the fractional metric dimension of corona product graphs and lexicographic product graphs
, 2012 A vertex $x$ in a graph $G$ resolves two vertices $u$, $v$ of $G$ if the distance between $u$ and $x$ is not equal to the distance between $v$ and $x$. A function $g$ from the vertex set of $G$ to $[0,1]$ is a resolving function of $G$ if $g(R_G\{u,v\})\geq 1$ for any two distinct vertices $u$ and $v$, where $R_G\{u,v\}$ is the set of vertices ...
Feng, Min, Wang, Kaishun
openaire +2 more sources
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
On an inverse problem for fractional connection Laplacians
, 2023 Thesis (Ph.D.)--University of Washington, 2023Classical inverse problems seek to determine the unknown coefficients of a PDE from boundary or local measurements of solutions.
Chien, Chun-Kai
core
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source