Results 61 to 70 of about 61,286 (267)

2D Fractional Supersymmetry for Rational Conformal Field Theory. Application for Third-Integer Spin States [PDF]

open access: yes, 1996
A 2D- fractional supersymmetry theory is algebraically constructed. The Lagrangian is derived using an adapted superspace including, in addition to a scalar field, two fields with spins 1/3,2/3.
A. Perez   +47 more
core   +4 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Identifying codes in vertex-transitive graphs and strongly regular graphs [PDF]

open access: yes, 2015
We consider the problem of computing identifying codes of graphs and its fractional relaxation. The ratio between the size of optimal integer and fractional solutions is between 1 and 2ln(vertical bar V vertical bar) + 1 where V is the set of vertices of
Gravier, Sylvain   +4 more
core   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Geodesically Complete Metrics Induce Boundary Non-locality in Holography: Consequences for the Entanglement Entropy

open access: yes, 2016
We show explicitly that the full structure of IIB string theory is needed to remove the non-localities that arise in boundary conformal theories that border hyperbolic spaces on AdS$_5$.
La Nave, Gabriele, Phillips, Philip W.
core   +1 more source

The Moduli Space of BPS Domain Walls [PDF]

open access: yes, 2002
N=2 SQED with several flavors admits multiple, static BPS domain wall solutions. We determine the explicit two-kink metric and examine the dynamics of colliding domain walls.
A. Alonso Izquierdo   +36 more
core   +2 more sources

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Introduction to multifractional spacetimes

open access: yes, 2012
We informally review the construction of spacetime geometries with multifractal and, more generally, multiscale properties. Based on fractional calculus, these continuous spacetimes have their dimension changing with the scale; they display discrete ...
Calcagni, Gianluca
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

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