Results 121 to 130 of about 14,195,801 (251)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Fractional model for Middle East respiratory syndrome coronavirus on a complex heterogeneous network. [PDF]
Sci Rep, 2022 El-Saka HAA, Obaya I, Lee S, Jang B.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Fractional growth model of abalone length
Partial Differential Equations in Applied MathematicsThis paper uses fractional growth model modified from McKendrick equation to describe the growth of abalone length. The fractional model is analyzed by generalized differential transform method to obtain Taylor’s series which is then used to predict the ...
Marliadi Susanto +2 more
doaj +1 more source
MHD Free convection flows of Jeffrey fluid with Prabhakar-like fractional model subject to generalized thermal transport. [PDF]
Sci Rep, 2023 Siddique I, Adrees R, Ahmad H, Askar S.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Stability Analysis of an Extended SEIR COVID-19 Fractional Model with Vaccination Efficiency. [PDF]
Comput Math Methods Med, 2022 Wali M, Arshad S, Huang J.
europepmc +1 more source
Radar matched filtering using the fractional fourier transform [PDF]
, 2010 -A matched filter is the optimal linear filter for maximizing the signal to noise ratio (SNR) in the presence of additive noise. Matched filters are commonly used in radar systems where the transmitted signal is known and may be used as a replica to be ...
Clemente, Carmine +2 more
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