Results 131 to 140 of about 649,336 (290)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A novel fractional model for the projection of households using wealth index quintiles. [PDF]
PLoS One, 2022 Ahmad S, Javeed S, Raza S, Baleanu D.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Fractional model analysis of COVID-19 spread based on big data platform. [PDF]
Heliyon, 2023 Li Y, Liu X.
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Fractional growth model of abalone length
Partial Differential Equations in Applied MathematicsThis paper uses fractional growth model modified from McKendrick equation to describe the growth of abalone length. The fractional model is analyzed by generalized differential transform method to obtain Taylor’s series which is then used to predict the ...
Marliadi Susanto +2 more
doaj +1 more source
Caputo-Fabrizio fractional model of MHD second grade fluid with Newtonian heating and heat generation. [PDF]
Sci Rep, 2022 Sehra +5 more
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Fractional model for Middle East respiratory syndrome coronavirus on a complex heterogeneous network. [PDF]
Sci Rep, 2022 El-Saka HAA, Obaya I, Lee S, Jang B.
europepmc +1 more source