Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Parameter Estimation Method For Fractional Order PNGV Battery Model
Turkish Journal of Electrical Power and Energy SystemsAmong the different types of batteries, Li-ion batteries are the most preferred type due to the performance and safety features they provide. Battery management systems are needed to get convenient performance from this kind of battery and to extend the ...
Emre Balkış, Ekrem Düven
doaj +1 more source
MHD Free convection flows of Jeffrey fluid with Prabhakar-like fractional model subject to generalized thermal transport. [PDF]
Sci Rep, 2023 Siddique I, Adrees R, Ahmad H, Askar S.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Stability Analysis of an Extended SEIR COVID-19 Fractional Model with Vaccination Efficiency. [PDF]
Comput Math Methods Med, 2022 Wali M, Arshad S, Huang J.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
ABAQUS Subroutine-Based Implementation of a Fractional Consolidation Model for Saturated Soft Soils
Fractal and FractionalThis paper presents a finite element implementation of a fractional rheological consolidation model in ABQUS, in which the fractional Merchant model governs the mechanical behavior of the soil skeleton, and the water flow is controlled by the fractional ...
Tao Zeng, Tao Feng, Yansong Wang
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A fractional model of magnetohydrodynamics Oldroyd-B fluid with couple stresses, heat and mass transfer: A comparison among Non-Newtonian fluid models. [PDF]
Heliyon, 2023 Arif M +3 more
europepmc +1 more source