Results 101 to 110 of about 10,348 (263)
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
On Mikusinski's operators of fractional integration
, 1975 In the field F of convolution quotients, b∝ is the operator of integration of fractional order ∝ and b∝ f Is the Riemann - Liouville integral of order ∝ of f. In this paper we give a generalization of this operator, which is denoted as b∝,va . Some particular cases are mentioned and the inverse operator is obtained.
Batting, A., Kalla, S. L.
openaire +2 more sources
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
World Journal of Applied Science & TechnologyVariation of parameters is obtained on the application of nearness properties of operators to a natural perturbation of nonlinear fractional operators. The nearness principle yields solvability of difficult perturbed nonlinear fractional integral equations via variation of parameters.
Udo-Utun, X., Edet, U., Johnson, U.
openaire +2 more sources
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Generalized multiplicative h-fractional integrals and derivatives with Hermite-Hadamard inequality
Journal of Inequalities and ApplicationsIn this study, we introduce new generalized multiplicative h-fractional integral and h-fractional derivative operators by employing multiplicative calculus within the framework of fractional analysis.
Umut Bas, Huseyin Yildirim
doaj +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source