Results 101 to 110 of about 755,580 (294)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Physical and geometrical interpretation of fractional operators

open access: yes, 1998
In this paper an interpretation of fractional operators in the time domain is given. The interpretation is based on the four concepts of fractal geometry, linear filters, construction of a Cantor set and physical realisation of fractional operators.
M. Moshrefi-Torbati   +3 more
core   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Mean value properties of fractional second order operators

open access: yes, 2015
In this paper we introduce a method to define fractional operators using mean value operators. In particular we discuss a geometric approach in order to construct fractional operators. As a byproduct we define fractional linear operators in Carnot groups,
FERRARI, FAUSTO
core   +1 more source

Weighted inequalities for fractional integral operators with kernel satisfying Hörmander type conditions [PDF]

open access: yes, 2011
In this paper we study inequalities with weights for fractional operators Tαgiven by convolution with a kernel Kαwhich is supposed to satisfy some size condition and a fractional Hörmander type condition.
Riveros, Maria Silvina   +7 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A New k-Fractional Integral Operators and their Applications

open access: yes, 2021
In this paper, we present a new k-fractional integral oper-ators involvingparameters °; ¸ analogous to the Riemann-Liouville k-fractional integral.
Ghulam Farid; Department of Mathematics, University of Agriculture Faisalabad,   +1 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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