Results 121 to 130 of about 755,580 (294)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
A comparative study of a thermoelastic problem for an infinite rigid cylinder with thermal properties using a new heat conduction model including fractional operators without non-singular kernels. [PDF]
Arch Appl Mech, 2022 Abouelregal AE.
europepmc +1 more source
World Journal of Applied Science & TechnologyVariation of parameters is obtained on the application of nearness properties of operators to a natural perturbation of nonlinear fractional operators. The nearness principle yields solvability of difficult perturbed nonlinear fractional integral equations via variation of parameters.
Udo-Utun, X., Edet, U., Johnson, U.
openaire +2 more sources
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
A Study of Composition Formulas for the Unified Fractional Integral Operators
, 2015 [[abstract]]In the present paper we derive three new and interesting composition formulas for a general class of fractional integral operators involving the product of a general class of polynomials, a general sequence of functions and a multivariable H ...
Sharma, Arti, Jain, Rashmi
core
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Optimal control of fractional systems: a diffusive formulation [PDF]
, 2010 Optimal control of fractional linear systems on a finite horizon can be classically formulated using the adjoint system. But the adjoint of a causal fractional integral or derivative operator happens to be an anti-causal operator: hence, the adjoint ...
Matignon, Denis
core
An application of multiple Erdélyi–Kober fractional integral operators to establish new inequalities involving a general class of functions [PDF]
This research aims to develop generalized fractional integral inequalities by utilizing multiple Erdélyi–Kober (E–K) fractional integral operators. Using a set of j, with (j?N) positively continuous and decaying functions in the finite interval a?t?x ...
Qureshi, Sania +9 more
core +1 more source