Results 121 to 130 of about 16,663 (301)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Operator dimension parity fractionalization

open access: yesJournal of High Energy Physics
A bstract Lorentz invariant quantum field theories (QFTs) with fermions in four spacetime dimensions (4D) have a ℤ 4 symmetry provided there exists a basis of operators in the QFT where all ...
openaire   +3 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Proposal for the application of fractional operators in polynomial regression models to enhance the determination coefficient R2 on unseen data

open access: yes
Since polynomial regression models are generally quite reliable for data that can be handled using a linear system, it is important to note that in some cases, they may suffer from overfitting during the training phase.
Brambila Paz, Fernando   +2 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Generalized Non-Homogeneous Morrey Spaces And Olsen Inequality

open access: yes, 2008
In this paper, we shall discuss some properties of generalized non-homogeneous Morrey spaces. In addition, we will also prove the Olsen inequality in the non-homogeneous setting.
H. Gunawan, .   +3 more
core  

An application of multiple Erdélyi–Kober fractional integral operators to establish new inequalities involving a general class of functions

open access: yes
This research aims to develop generalized fractional integral inequalities by utilizing multiple Erdélyi–Kober (E–K) fractional integral operators. Using a set of j, with (j?N) positively continuous and decaying functions in the finite interval a?t?x ...
Qureshi, Sania   +9 more
core   +1 more source

Electrochemical Evaluation of Compressed Selective Laser Melted AlSi7Mg and AlSi10Mg Alloys in Chloride Environment

open access: yesAdvanced Engineering Materials, EarlyView.
The corrosion performance of AlSi7Mg and AlSi10Mg alloys produced through selective laser melting (SLM) was examined under compressive stress in a chloride environment. Electrochemical analyses, including open‐circuit potential (OCP), potentiodynamic polarization (CPP), and electrochemical impedance spectroscopy (EIS), were complemented by scanning ...
Femi John Akinfolarin   +2 more
wiley   +1 more source

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