Results 141 to 150 of about 755,580 (294)

Properties and Applications of Complex Fractal–Fractional Operators in the Open Unit Disk

A fractal–fractional calculus is presented in term of a generalized gamma function (ℓ−gamma function: Γℓ(.)). The suggested operators are given in the symmetric complex domain (the open unit disk).
Mansour F. Yassen, Yassen, Mansour F., Soheil Salahshour, Salahshour, Soheil, Ibrahim, Rabha W., Adel A. Attiya, Rabha W. Ibrahim, Attiya, Adel A.   +7 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Caputo fractional approximation by sublinear operators [PDF]

, 2018
Here we consider the approximation of functions by sublinear positive operators with applications to a big variety of Max-Product operators under Caputo fractional differentiability.
George A. Anastassiou
core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Incremental parameterized-kernel fractional operators: theory, novel Banach spaces, and machine learning applications

Ain Shams Engineering Journal
This paper presents a new class of Incremental Parameterized–Kernel (IPK) fractional derivative and integral operators that improve modeling of complex dynamical systems.
Tahir Ullah Khan, Christine Markarian
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Modelling the spread of COVID-19 with new fractal-fractional operators: Can the lockdown save mankind before vaccination? [PDF]

Chaos Solitons Fractals, 2020
Atangana A.
europepmc   +1 more source

A design methodology to enable sampling PLLs to synthesise fractional-N frequencies [PDF]

, 2011
A novel design methodology is proposed to enable sampling phase-locked loops (SPLL) to synthesise fractional-N frequencies. To date, SPLL can only generate integer-N frequencies.
Xu, Tao, Condon, Marissa, Linigyong, Shen   +2 more
core   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Applying fixed point methods and fractional operators in the modelling of novel coronavirus 2019-nCoV/SARS-CoV-2. [PDF]

Results Phys, 2020
Panda SK.
europepmc   +1 more source