Results 101 to 110 of about 11,089,487 (322)

Fourth order quasi-compact difference schemes for (tempered) space fractional diffusion equations [PDF]

open access: yes, 2014
The continuous time random walk (CTRW) underlies many fundamental processes in non-equilibrium statistical physics. When the jump length of CTRW obeys a power-law distribution, its corresponding Fokker-Planck equation has space fractional derivative ...
Deng, Weihua, Wu, Yujiang, Yu, Yanyan
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Numerical Methods for Solving Fractional Differential Equations [PDF]

open access: yes, 2018
Department of Mathematical SciencesIn this thesis, several efficient numerical methods are proposed to solve initial value problems and boundary value problems of fractional di???erential equations.
Kim, Keon Ho
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Fractional-Order LCL Filters: Principle, Frequency Characteristics, and Their Analysis

open access: yesFractal and Fractional
The fractional-order LCL filter, composed of two fractional-order inductors and one fractional-order capacitor, is a novel fractional-order π-type circuit introduced in recent years.
Junhua Xu   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Global Mittag–Leffler Stability and Stabilization Analysis of Fractional-Order Quaternion-Valued Memristive Neural Networks

open access: yesMathematics, 2020
This paper studies the global Mittag–Leffler stability and stabilization analysis of fractional-order quaternion-valued memristive neural networks (FOQVMNNs).
G. Rajchakit   +4 more
semanticscholar   +1 more source

Discretization of Fractional Order Differentiator and Integrator with Different Fractional Orders

open access: yesIntelligent Control and Automation, 2017
This paper is concerned with the discretization of the fractional-order differentiator and integrator, which is the foundation of the digital realization of fractional order controller. Firstly, the parameterized Al-Alaoui transform is presented as a general generating function with one variable parameter, which can be adjusted to obtain the ...
Qi Zhang   +3 more
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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