Results 91 to 100 of about 24,680,666 (254)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Numerical Analysis, Circuit Simulation, and Control Synchronization of Fractional-Order Unified Chaotic System

open access: yesMathematics, 2019
The traditional method of solving fractional chaotic system has the problem of low precision and is computationally cumbersome. In this paper, different fractional-order calculus solutions, the Adams prediction−correction method, the Adomian ...
Guohui Li, Xiangyu Zhang, Hong Yang
doaj   +1 more source

Diffusive representations for fractional Laplacian: systems theory framework and numerical issues [PDF]

open access: yes, 2009
Bridging the gap between an abstract definition of pseudo-differential operators, such as (-\Delta)^{\gamma} for - 1/2 < \gamma < 1/2, and a concrete way to represent them has proved difficult; deriving stable numerical schemes for such operators is not ...
Matignon, Denis
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Multi-order fractional nonlinear evolution equations system

open access: yesPartial Differential Equations in Applied Mathematics
In this paper, the existence and uniqueness of a solution to a multi-order fractional nonlinear evolution equations system are studied by applying Banach’s Fixed Point Theorem and some properties of solution operators associated with the system.
Bambang Hendriya Guswanto   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Projective Synchronization for a Class of Fractional-Order Chaotic Systems with Fractional-Order in the (1, 2) Interval

open access: yesEntropy, 2015
In this paper, a projective synchronization approach for a class of fractional-order chaotic systems with fractional-order 1 < q < 2 is demonstrated. The projective synchronization approach is established through precise theorization. To illustrate
Ping Zhou, Rongji Bai, Jiming Zheng
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

FRACTIONAL ORDER SYSTEM IDENTIFICATION BASED ON GENETIC ALGORITHMS [PDF]

open access: yesJournal of Engineering Science and Technology, 2013
System identification deals with estimating the plant parameters under control using input-output measuring data. Most of practical plants have fractional order dynamic properties which are based on integration and differentiation of noninteger order. In
MAZIN Z. OTHMAN, EMAD A. AL-SABAWI
doaj  

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