Results 81 to 90 of about 24,680,666 (254)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Analysis of Error-Based Switched Fractional-Order Adaptive Systems: An Error Model Approach
Fractal and FractionalSwitched adaptive laws for parameter estimation have been proposed in recent years to improve the balance between control energy and system performance in adaptive schemes, which is often a big issue when using traditional integer-order or fractional ...
Norelys Aguila-Camacho +3 more
doaj +1 more source
The Proposed Modified Liu System with Fractional Order
Advances in Mathematical Physics, 2013 The chaos in a new system with order 3 is studied. We have shown that this chaotic system again will be chaotic when the order of system is less than 3.
Alireza K. Golmankhaneh +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
On Non-Commensurate Fractional-Order System Control
MathematicsThe control systems for models described by non-commensurate fractional-order differential equations are based on their transformation into large commensurate-order systems, which impose difficulties in determining control laws.
Mircea Ivanescu, Decebal Popescu
doaj +1 more source
Discrete-time model reference control schemes of milling forces using fractional order holds [PDF]
, 2007 Increasing competence makes to develop and implement more complex control schemes on manufacturing environments. In this paper, a discrete time model reference control for practical milling using different discretization of the continuous-time plant is ...
M. de la Sen +3 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
An Efficient Numerical Scheme for Solving a Fractional-Order System of Delay Differential Equations. [PDF]
Int J Appl Comput Math, 2022 Kumar M.
europepmc +1 more source
Dynamic Analysis of a Fractional-Order Economic Model: Chaos and Control
Fractal and FractionalFractional calculus in discrete-time is a recent field that has drawn much interest for dealing with multidisciplinary systems. A result of this tremendous potential, researchers have been using constant and variable-order fractional discrete calculus in
Ali Aloui +5 more
doaj +1 more source