Results 61 to 70 of about 97,065 (260)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A Fractional Order General Type-2 Fuzzy PID Controller Design Algorithm

IEEE Access, 2020
Fractional order PID controller was received attentions in control problems for it had 2 freedom adjustable parameters. Practices had proved that better results could be obtained by introduction of fractional order PID in control problems.
Jian Zhong Shi
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Recurrence analysis of fractional-order Lorenz system

MATEC Web of Conferences, 2018
The fractional derivative is increasingly used in modeling of nonlinear systems. Fractional-order systems often give better fit to the experimental results, especially for the systems in which memory effects or hysteresis play a significant role.
Rysak Andrzej, Gregorczyk Magdalena
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Fractional-order chaotic system with hyperbolic function

Advances in Mechanical Engineering, 2019
In this article, we study bistability, multiscroll, and symmetric properties of fractional-order chaotic system with cubic nonlinearity. The system is configured with hyperbolic function consisting of a parameter “ g .” By varying the parameter “ g ...
G Gugapriya, Prakash Duraisamy, Anitha Karthikeyan, B Lakshmi   +3 more
doaj   +1 more source

A Fractional-Order Resonant Wireless Power Transfer System With Inherently Constant Current Output

IEEE Access, 2020
Wireless power transfer (WPT) using magnetic-coupling resonant has been proved to be a promising transmission method. At present, most of the existing resonant WPT systems adopt integer-order inductors and capacitors.
Yanwei Jiang, Bo Zhang, Jiali Zhou
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Analysis of Error-Based Switched Fractional-Order Adaptive Systems: An Error Model Approach

Fractal and Fractional
Switched adaptive laws for parameter estimation have been proposed in recent years to improve the balance between control energy and system performance in adaptive schemes, which is often a big issue when using traditional integer-order or fractional ...
Norelys Aguila-Camacho, Javier Alejandro Gallegos, Yangquan Chen, Juan Carlos Travieso-Torres   +3 more
doaj   +1 more source