Results 51 to 60 of about 4,216 (305)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Direct Power Series Approach for Solving Nonlinear Initial Value Problems

Axioms, 2023
In this research, a new approach for solving fractional initial value problems is presented. The main goal of this study focuses on establishing direct formulas to find the coefficients of approximate series solutions of target problems.
Emad Salah, Rania Saadeh, Ahmad Qazza, Raed Hatamleh   +3 more
doaj   +1 more source

Solutions of Sequential Conformable Fractional Differential Equations around an Ordinary Point and Conformable Fractional Hermite Differential Equation [PDF]

British Journal of Applied Science & Technology, 2015
In this work, we give the power series solutions around an ordinary point, in the case of variable coefficients, homogeneous sequential linear conformable fractional differential equations of order 2 . Further, we introduce the conformable fractional Hermite differential equations, conformable fractional Hermite polynomials and basic properties of ...
GÖKDOĞAN, AHMET, ÜNAL, EMRAH, ÇELİK, Ercan   +2 more
openaire   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Exact solutions for STO and (3+1)-dimensional KdV-ZK equations using G′G2-expansion method

Results in Physics, 2017
This article deals with finding some exact solutions of nonlinear fractional differential equations (NLFDEs) by applying a relatively new method known as G′G2-expansion method.
Sadaf Bibi, Syed Tauseef Mohyud-Din, Rahmat Ullah, Naveed Ahmed, Umar Khan   +4 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The closed-form solution by the exponential rational function method for the nonlinear variable-order fractional differential equations

Frontiers in Physics
The symmetry features of fractional differential equations allow effective explanation of physical and biological phenomena in nature. The generalized form of the fractional differential equations is the variable-order fractional differential equations ...
Mashael M. ALBaidani, Umair Ali, Abdul Hamid Ganie   +2 more
doaj   +1 more source

Conformable Laplace Transform of Fractional Differential Equations

Axioms, 2018
In this paper, we use the conformable fractional derivative to discuss some fractional linear differential equations with constant coefficients.
Fernando S. Silva, Davidson M. Moreira, Marcelo A. Moret   +2 more
doaj   +1 more source