Results 71 to 80 of about 4,114 (261)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Exact solutions for a class of space-time fractional mixed (1+1)-dimensional KdV equations

四川大学学报. 自然科学版, 2018
Exact solutions of a class of space-time fractional mixed (1+1)-dimensional KdV equations with modified Riemann-Liouville fractional derivative are considered.
LI Lin-Fang, SHU Ji, WEN Hui-Xia
doaj  

Regarding on the exact solutions for the nonlinear fractional differential equations

Open Physics, 2016
In this work, we have considered the modified simple equation (MSE) method for obtaining exact solutions of nonlinear fractional-order differential equations.
Kaplan Melike, Koparan Murat, Bekir Ahmet   +2 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Dirac Factorization, Partial/Ordinary Differential Equations and Fractional Calculus

Symmetry
The Dirac factorization method (DFM) is the key feature of the present investigation. It is addressed to the relevant use in diverse fields of research, regarding, e.g., the handling of pseudo-operators arising in quantum mechanics and fractional calculus.
Giuseppe Dattoli, Emanuele Di Palma, Alessandro Curcio   +2 more
openaire   +2 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

New Perturbation–Iteration Algorithm for Nonlinear Heat Transfer of Fractional Order

Fractal and Fractional
Ordinary differential equations have recently been extended to fractional equations that are transformed using fractional differential equations. These fractional equations are believed to have high accuracy and low computational cost compared to ...
Mohammad Abdel Aal
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Asymptotic Behavior of Solutions to Nonlinear Fractional Differential Equations

Mathematical Modelling and Analysis, 2016
It is known that, under certain conditions, solutions of some ordinary differential equations of first, second or even higher order are asymptotic to polynomials as time goes to infinity.
Mohammed D. Kassim, Khaled M. Furati, Nasser-Eddine Tatar   +2 more
doaj   +1 more source