Results 81 to 90 of about 4,114 (261)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Theoretical investigation on fractal–fractional nonlinear ordinary differential equations

Nonlinear Analysis: Real World Applications
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Abdon Atangana, Seda İğret Araz
openaire   +2 more sources

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Analyzing fuzzy fractional Degasperis–Procesi and Camassa–Holm equations with the Atangana–Baleanu operator

Open Physics
This article presents a new approach for solving the fuzzy fractional Degasperis–Procesi (FFDP) and Camassa–Holm equations using the iterative transform method (ITM). The fractional Degasperis–Procesi (DP) and Camassa–Holm equations are extended from the
Alshehry Azzh Saad, Yasmin Humaira, Shah Manzoor Ali, Shah Rasool   +3 more
doaj   +1 more source

A note on Riccati-Bernoulli Sub-ODE method combined with complex transform method applied to fractional differential equations

Nonlinear Engineering, 2018
In this paper, the fractional derivatives in the sense of modified Riemann–Liouville and the Riccati-Bernoulli Sub-ODE method are used to construct exact solutions for some nonlinear partial fractional differential equations via the nonlinear fractional ...
Abdelrahman Mahmoud A.E.
doaj   +1 more source

Picard’s Iterative Method for Caputo Fractional Differential Equations with Numerical Results

Mathematics, 2017
With fractional differential equations (FDEs) rising in popularity and methods for solving them still being developed, approximations to solutions of fractional initial value problems (IVPs) have great applications in related fields. This paper proves an
Rainey Lyons, Aghalaya S. Vatsala, Ross A. Chiquet   +2 more
doaj   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Chebyshev Finite Difference Method for Fractional Boundary Value Problems

Journal of Mathematical Extension, 2015
This paper presents a numerical method for fractional differential equations using Chebyshev finite difference method. The fractional derivatives are described in the Caputo sense.
Boundary
doaj  

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source