Results 61 to 70 of about 2,923,613 (246)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Numerical solution methods for fractional partial differential equations [PDF]

open access: yes, 2017
Fractional partial differential equations have been developed in many different fields such as physics, finance, fluid mechanics, viscoelasticity, engineering and biology. These models are used to describe anomalous diffusion.
Osman, Sheelan Abdulkader
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Solitary wave solutions of the conformable space–time fractional coupled diffusion equation

open access: yesPartial Differential Equations in Applied Mathematics
In the realm of spatio-temporal fractional dynamics in a predator–prey system, we investigate fractional solitary wave-like solutions using the conformable space–time fractional coupled diffusion equation.
K. Manikandan   +3 more
doaj   +1 more source

A note on exp-function method combined with complex transform method applied to fractional differential equations

open access: yesAdvances in Nonlinear Analysis, 2015
In this article, the fractional derivatives in the sense of modified Riemann–Liouville and the exp-function method are used to construct exact solutions for some nonlinear partial fractional differential equations via the nonlinear fractional Liouville ...
Guner Ozkan, Bekir Ahmet, Bilgil Halis
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Well-posedness of a class of singular Volterra integral equations on the L^p (p ≥1) space

open access: yes四川大学学报. 自然科学版, 2022
Motivated by fractional differential equations, we consider the well-posedness of a class of singular Volterra integral equations on the L^p (p ≥1) space by using the fixed point theorem, generalize and improve the known results.
ZHENG Meng-Liang
doaj  

The General Fractional Derivative and Related Fractional Differential Equations

open access: yesMathematics, 2020
In this survey paper, we start with a discussion of the general fractional derivative (GFD) introduced by A. Kochubei in his recent publications. In particular, a connection of this derivative to the corresponding fractional integral and the Sonine ...
Yuri Luchko, Masahiro Yamamoto
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Optimal error estimates of spectral Petrov-Galerkin and collocation methods for initial value problems of fractional differential equations

open access: yes, 2015
We present optimal error estimates for spectral Petrov-Galerkin methods and spectral collocation methods for linear fractional ordinary differential equations with initial value on a finite interval.
Zeng, F., Zhang, Z., Em Karniadakis, G.
core   +1 more source

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