Results 61 to 70 of about 51,039 (280)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Exact solutions for STO and (3+1)-dimensional KdV-ZK equations using G′G2-expansion method

open access: yesResults in Physics, 2017
This article deals with finding some exact solutions of nonlinear fractional differential equations (NLFDEs) by applying a relatively new method known as G′G2-expansion method.
Sadaf Bibi   +4 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Conformable Laplace Transform of Fractional Differential Equations

open access: yesAxioms, 2018
In this paper, we use the conformable fractional derivative to discuss some fractional linear differential equations with constant coefficients.
Fernando S. Silva   +2 more
doaj   +1 more source

Numerical modeling of a time-fractional Burgers equation [PDF]

open access: yes, 2017
A fractional time derivative is introduced into Burgers equation to model losses of nonlinear waves arising in acoustics. A diffusive representation of the fractional derivative replaces the non-local operator by a continuum of memory variables that ...
Lombard, Bruno, Matignon, Denis
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

About Some Possible Implementations of the Fractional Calculus

open access: yesMathematics, 2020
We present a partial panoramic view of possible contexts and applications of the fractional calculus. In this context, we show some different applications of fractional calculus to different models in ordinary differential equation (ODE) and partial ...
María Pilar Velasco   +5 more
doaj   +1 more source

On the Existence and Stability of Variable Order Caputo Type Fractional Differential Equations

open access: yesFractal and Fractional, 2022
In the theory of differential equations, the study of existence and the uniqueness of the solutions are important. In the last few decades, many researchers have had a keen interest in finding the existence–uniqueness solution of constant fractional ...
Shahzad Sarwar
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The closed-form solution by the exponential rational function method for the nonlinear variable-order fractional differential equations

open access: yesFrontiers in Physics
The symmetry features of fractional differential equations allow effective explanation of physical and biological phenomena in nature. The generalized form of the fractional differential equations is the variable-order fractional differential equations ...
Mashael M. ALBaidani   +2 more
doaj   +1 more source

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