Results 61 to 70 of about 4,114 (261)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Solitary wave solutions of the conformable space–time fractional coupled diffusion equation

Partial Differential Equations in Applied Mathematics
In the realm of spatio-temporal fractional dynamics in a predator–prey system, we investigate fractional solitary wave-like solutions using the conformable space–time fractional coupled diffusion equation.
K. Manikandan, N. Serikbayev, D. Aravinthan, K. Hosseini   +3 more
doaj   +1 more source

A note on exp-function method combined with complex transform method applied to fractional differential equations

Advances in Nonlinear Analysis, 2015
In this article, the fractional derivatives in the sense of modified Riemann–Liouville and the exp-function method are used to construct exact solutions for some nonlinear partial fractional differential equations via the nonlinear fractional Liouville ...
Guner Ozkan, Bekir Ahmet, Bilgil Halis
doaj   +1 more source

The General Fractional Derivative and Related Fractional Differential Equations

Mathematics, 2020
In this survey paper, we start with a discussion of the general fractional derivative (GFD) introduced by A. Kochubei in his recent publications. In particular, a connection of this derivative to the corresponding fractional integral and the Sonine ...
Yuri Luchko, Masahiro Yamamoto
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Well-posedness of a class of singular Volterra integral equations on the L^p (p ≥1) space

四川大学学报. 自然科学版, 2022
Motivated by fractional differential equations, we consider the well-posedness of a class of singular Volterra integral equations on the L^p (p ≥1) space by using the fixed point theorem, generalize and improve the known results.
ZHENG Meng-Liang
doaj  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Theories and applications of the inverse fractional natural transform method

Advances in Difference Equations, 2018
In this paper, we propose a new method called the inverse fractional natural transform method (IFNTM). We present theoretical results and apply them to obtain approximate solutions of linear fractional ordinary differential equations (LFODEs) and partial
Mahmoud S. Rawashdeh, Hadeel Al-Jammal
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source