Results 81 to 90 of about 41,489 (237)

Existence of solutions for non-local elliptic systems with Hardy-Littlewood-Sobolev critical nonlinearities

Electronic Journal of Differential Equations, 2019
In this work, we establish the existence of solutions for the nonlinear nonlocal system of equations involving the fractional Laplacian, \begin{gather*} \begin{aligned} (-\Delta)^s u & = au+bv+\frac{2p}{p+q}\int_{\Omega}\frac{|v(y)|^q}{|x-y|^\mu}dy|
Yang Yang, Qian Yu Hong, Xudong Shang
doaj  

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Chiral Supramolecular Templating Enables Tunable Second‐Harmonic Generation in Hybrid Zinc Thiocyanates

Angewandte Chemie, EarlyView.
Chiral supramolecular templates derived from natural amino acids direct the spatial organization of SHG‐active [Zn(SCN)4]2− units, enabling diverse second‐harmonic generation in hybrid zinc thiocyanates. ABSTRACT Chiral organic molecules have been widely used to construct hybrid nonlinear optical (NLO) materials with second‐harmonic generation (SHG ...
Xuemei Wen, Qinglan Zhong, Gangji Yi, Guohong Zou, Jianli Wang, Zhien Lin, Kang Min Ok   +6 more
wiley   +2 more sources

Normalized solutions for a class of fractional Choquard equations with mixed nonlinearities

Demonstratio Mathematica
In this paper we study the following fractional Choquard equation with mixed nonlinearities:(−Δ)su=λu+αIμ∗|u|q|u|q−2u+Iμ∗|u|p|u|p−2u,x∈RN,∫RN|u|2dx=c2>0.
Chen Shaoxiong, Yang Zhipeng, Zhang Xi
doaj   +1 more source

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

Advanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang, Liang Qiu, Xingbang Ruan, Yihan Shi, Ye Wang, Hanwen Li, Kai Zhang, Kangwu Chen   +7 more
wiley   +1 more source

A de‐novo Approach Towards Divergent [3+2π/σ] Photocycloadditions of Nitrones via Assembly‐Controlled Kinetic Electron Transfer Gating

Angewandte Chemie, EarlyView.
A metal‐free photocatalytic platform converts nitrones into 4‐isoxazolines and oxa–aza–bicycloheptanes through divergent [3+2π/σ] cycloadditions. Assembly‐controlled kinetic electron transfer gating dictates substrate activation, enabling selective reactivity beyond thermodynamic expectations.
Nayan Saha, Rajesh Kancherla, Jorge Escorihuela, Shana Chandran, Mrinal K. Bera, Magnus Rueping, Burkhard König   +6 more
wiley   +2 more sources

Uniqueness of positive solutions for fractional q-difference boundary-value problems with p-Laplacian operator

Electronic Journal of Differential Equations, 2013
In this article, we study the fractional q-difference boundary-value problems with p-Laplacian operator $$displaylines{ D_{q}^{gamma}(phi_p(D_{q}^{alpha}u(t))) + f(t,u(t))=0, quad 0 < t < 1, ; 2 < alpha < 3,cr u(0) = (D_qu)(0) = 0, quad (D_qu)(1 ...
Fenghua Miao, Sihua Liang
doaj  

Positive solutions to fractional boundary-value problems with p-Laplacian on time scales

Boundary Value Problems, 2018
In this article, we consider the following boundary-value problem of nonlinear fractional differential equation with p-Laplacian operator: Dα(ϕp(Dαu(t)))=f(t,u(t)),t∈[0,1]T,u(0)=u(σ(1))=Dαu(0)=Dαu(σ(1))=0, $$\begin{aligned}& D^{\alpha }\bigl(\phi_{p ...
Kai Sheng, Wei Zhang, Zhanbing Bai
doaj   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

High‐Responsivity and Fast‐Response Organic Phototransistor Based on Dinaphtho[2,3‐b:2′,3′‐f]Thieno[3,2‐b]Thiophene

Advanced Electronic Materials, EarlyView.
Low‐temperature Al/Al2O3/DNTT/Au organic phototransistors fabricated on flexible PEN combine high responsivity to blue light (≈250 A W−1 at 39 nW cm−2) with detectable modulated photoresponse up to 150 kHz, making them promising for ultra‐low‐light sensing and moderate‐speed optical links.
Antonio Caldarelli, Antonio Vettoliere, Paolo Scotto Di Vettimo, Marcello Campajola, Gino Giusi, Vincenzo Izzo, Alberto Aloisio, Ettore Sarnelli   +7 more
wiley   +1 more source