Results 41 to 50 of about 8,378 (264)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Journal of Inequalities and Applications, 2019 A new class of (not necessarily differentiable) multiobjective fractional programming problems with E-differentiable functions is considered. The so-called parametric E-Karush–Kuhn–Tucker necessary optimality conditions and, under E-convexity hypotheses,
Tadeusz Antczak, Najeeb Abdulaleem
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FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
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Sensitivity analysis in piecewise linear fractional programming problem with non-degenerate optimal solution [PDF]
Opuscula Mathematica, 2009 In this paper, we study how changes in the coefficients of objective function and the right-hand-side vector of constraints of the piecewise linear fractional programming problems affect the non-degenerate optimal solution.
Behrouz Kheirfam
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Duality and Sensitivity Analysis for Fractional Programs [PDF]
Operations Research, 1976 In this paper we consider algorithms, duality and sensitivity analysis for optimization problems, called fractional, whose objective function is the ratio of two real-valued functions. We discuss a procedure suggested by Dinkelbach for solving the problem, its relation to certain approaches via variable transformations, and a variant of the procedure ...
Gabriel R. Bitran, Thomas L. Magnanti
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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A dynamic programming approach to adaptive fractionation [PDF]
Physics in Medicine and Biology, 2012 We conduct a theoretical study of various solution methods for the adaptive fractionation problem. The two messages of this paper are: (i) dynamic programming (DP) is a useful framework for adaptive radiation therapy, particularly adaptive fractionation, because it allows us to assess how close to optimal different methods are, and (ii) heuristic ...
Ramakrishnan, Jagdish +3 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Generalized Heptagonal Membership Function for Fully Fuzzy Linear Fractional Programming Problems
Ibn Al-Haitham Journal for Pure and Applied SciencesIdentifying the optimum solution that satisfies the restrictions and maximizes or minimizes the objective function is the aim of fully fuzzy fractional programming (FFFLP). Due to the inclusion of both fuzzy parameters and fractional variables, this
Israa Hadi, Iden H. Al Kanani
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