Results 61 to 70 of about 8,378 (264)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Zanco Journal of Pure and Applied SciencesThe revised harmonious fuzzy technique (RHFT) is a method used to solve fuzzy optimization problems. It was capitalized as an extension of the classical linear programming technique to handle constraints and objectives that are fuzzy. The harmonious
Maher A. Nawkhass
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Fractional programming in cooperative games [PDF]
, 2013 Cooperation of individuals or institutions is often coupled with benefits that can be regarded as the monetary worth or outcome of the cooperation. Therefore, the problem naturally arises how to allocate the total outcome among institutions or individuals in a fair way. Such allocation problems are studied within cooperative game theory. A general idea
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A linear fractional bilevel programming problem with multichoice parameters
Croatian Operational Research Review, 2017 A bilevel programming problem (BLPP) is a hierarchical optimization problem where the constraint region of the upper level is implicitly determined by the lower level optimization problem.
Ritu Arora, Kavita Gupta
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Genetic algorithmic based approach for multiple-objective probabilistic fractional programming problem involving discrete random variables. [PDF]
PLoS One, 2022 Belay B, Abebaw A.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Web-oriented software for solving linear programming problems by graphical method
CTE Workshop Proceedings, 2015 The aim of work is to create web-oriented software for solving mathematical programming problems by graphical methods. Object of research is graphical methods for solving some mathematical programming problems.
E. V. Zaloyko, Yu. V. Tryus
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Efficiency and generalized concavity for multi-objective set-valued programming
Journal of Numerical Analysis and Approximation Theory, 2003 The purpose of this paper is to give sufficient conditions of generalized concavity type for a local (weakly) efficient solution to be a global (weakly) efficient solution for a vector maximization set-valued programming problem.
Ş. Ţigan, I.M. Stancu-Minasian
doaj +2 more sources