Results 61 to 70 of about 8,445 (264)

A Proposal to the Solution of Multiobjective Linear Fractional Programming Problem

open access: yesAbstract and Applied Analysis, 2013
We have proposed a new solution to the Multiobjective Linear Fractional Programming Problem (MOLFPP). The proposed solution is based on a theorem that deals with nonlinear fractional programming with single objective function and studied in the work by ...
Nuran Güzel
doaj   +1 more source

Fractional programming in cooperative games [PDF]

open access: yes, 2013
Cooperation of individuals or institutions is often coupled with benefits that can be regarded as the monetary worth or outcome of the cooperation. Therefore, the problem naturally arises how to allocate the total outcome among institutions or individuals in a fair way. Such allocation problems are studied within cooperative game theory. A general idea
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Revised Harmonious Fuzzy Technique for Solving Fully Fuzzy Multi-Objective Linear Fractional Programming Problems

open access: yesZanco Journal of Pure and Applied Sciences
    The revised harmonious fuzzy technique (RHFT) is a method used to solve fuzzy optimization problems. It was capitalized as an extension of the classical linear programming technique to handle constraints and objectives that are fuzzy. The harmonious
Maher A. Nawkhass
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

A linear fractional bilevel programming problem with multichoice parameters

open access: yesCroatian Operational Research Review, 2017
A bilevel programming problem (BLPP) is a hierarchical optimization problem where the constraint region of the upper level is implicitly determined by the lower level optimization problem.
Ritu Arora, Kavita Gupta
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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