Results 71 to 80 of about 8,668,074 (299)

The fractional chromatic number of triangle-free subcubic graphs [PDF]

, 2014
Heckman and Thomas conjectured that the fractional chromatic number of any triangle-free subcubic graph is at most 14 / 5. Improving on estimates of Hatami and Zhu and of Lu and Peng, we prove that the fractional chromatic number of any triangle-free ...
Král’, Daniel, Kaiser, Tomáš, Ferguson, David G. (Researcher in mathematics), Králʼ, Daniel, Kaiser, Thomáš, Ferguson, David G.   +5 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Evaluation of the volume and volume fraction of the lateral ventricles in the Parkinsonism

Journal of Experimental and Clinical Medicine, 2014
Parkinson’s disease (PD) commonly begins in late middle age and the course is slowly progressive. Ventricular enlargement, a nonspecific measure of brain atrophy, has been associated with PD. The aim of this study is to perform the measurements of the cerebral hemispheres and lateral ventricles using magnetic resonance imaging (MRI) in combination with
ACAR GÜDEK, Meltem, ELFAKI, Amani, OZDEMIR, Fikri, CAMLIDAG, Ilkay, ALTUNSOY, Emrah, SAHIN, Bunyamin   +5 more
openaire   +3 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Fractional location problems [PDF]

In this paper we analyze some variants of the classical uncapacitated facility location problem with a ratio as an objective function. Using basic concepts and results of fractional programming, we identify a class of one-level fractional location ...
Frenk, J.B.G., Gromicho, J.A.S., Barros, A.I.   +2 more
core  

Volume Management in the Critically Ill Patient with Acute Kidney Injury

Critical Care Research and Practice, 2013
Acute kidney injury (AKI) frequently occurs in the setting of critical illness and its management poses a challenge for the intensivist. Optimal management of volume status is critical in the setting of AKI in the ICU patient.
Mary Labib, Raeesa Khalid, Akram Khan, Supriya Khan   +3 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Fractional boundary value problems: Analysis and numerical methods [PDF]

, 2011
This is the author's PDF of an article published in Fractional Calculus and Applied Analysis 2011. The original publication is available at www.springerlink.comThis journal article discusses nonlinear boundary value problems.Fundacao para a Ciencia e ...
M. Luísa Morgado, Ford, Neville J., Morgado, Maria L., Neville J. Ford   +3 more
core   +1 more source