Results 11 to 20 of about 1,704,060 (353)
The Science of Fracture Healing
Journal of Orthopaedic Trauma, 2005 Fracture healing is a unique repair process in which the events of endochondral and intramembranous bone formation follow a specific time sequence. There are many ways in which these events can be disrupted, leading to unsuccessful fracture healing. This article summarizes the series of cellular and molecular events that take place in the process of ...
Thomas A. Einhorn
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The effect of favipiravir on fracture healing. [PDF]
Acta Orthop Traumatol TurcThe aim of this study was to evaluate the effects of favipiravir on fracture healing. Forty-eight female rats which had a femur fracture with intramedullary Kirschner wire fixation performed were divided into 6 groups; 2 control groups (C1, C2) and 4 experimental groups (F1, F2, F3, F4). The control groups (C1, C2) received physiological saline by oral
Sabır MA +3 more
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Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence.
Endocrine reviews, 2022 Over 2.1 million age-related fractures occur in the United States annually, resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of bone structure is associated with impaired bone healing. Fracture healing is a dynamic
D. Saul, S. Khosla
semanticscholar +1 more source
Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing
International Journal on Biological Sciences, 2022 The biomechanical environment plays a dominant role in fracture healing, and Piezo1 is regarded as a major mechanosensor in bone homeostasis. However, the role of Piezo1 in fracture healing is not yet well characterized.
Yunlu Liu +11 more
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Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice
Journal of Clinical Investigation, 2022 Cellular senescence plays an important role in human diseases, including osteoporosis and osteoarthritis. Senescent cells (SCs) produce the senescence-associated secretory phenotype to affect the function of neighboring cells and SCs themselves.
Jiatong Liu +5 more
semanticscholar +1 more source
Gait Analysis to Monitor Fracture Healing of the Lower Leg
Bioengineering, 2023 Fracture healing is typically monitored by infrequent radiographs. Radiographs come at the cost of radiation exposure and reflect fracture healing with a time lag due to delayed fracture mineralization following increases in stiffness.
Elke Warmerdam +3 more
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Advancement of science, 2021 The neuronal engagement of the peripheral nerve system plays a crucial role in regulating fracture healing, but how to modulate the neuronal activity to enhance fracture healing remains unexploited.
Jie Mi +16 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Bone fracture represents a significant problem in public health. State-of-the-art clinical study demonstrated that by correlating the stimulation amplitude and frequency directly to dynamic locomotion, biofeedback electrostimulation therapy ...
Guang Yao +12 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 The analysis of gait patterns and plantar pressure distributions via insoles is increasingly used to monitor patients and treatment progress, such as recovery after surgeries.
Christian Wolff +10 more
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Joint Cartilage in Long-Duration Spaceflight
Biomedicines, 2022 This review summarizes the current literature available on joint cartilage alterations in long-duration spaceflight. Evidence from spaceflight participants is currently limited to serum biomarker data in only a few astronauts.
Bergita Ganse +2 more
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