VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing [PDF]
, 2018 A significant number of fractures develop non‐union. Mesenchymal stem cell (MSC) therapy may be beneficial, however, this requires cell acquisition, culture and delivery. Endogenous mobilization of stem cells offers a non‐invasive alternative.
Blunn, G +3 more
core +3 more sources
Early pH Changes in Musculoskeletal Tissues upon Injury-Aerobic Catabolic Pathway Activity Linked to Inter-Individual Differences in Local pH [PDF]
, 2020 Local pH is stated to acidify after bone fracture. However, the time course and degree of acidification remain unknown. Whether the acidification pattern within a fracture hematoma is applicable to adjacent muscle hematoma or is exclusive to this ...
Berkmann, Julia C. +8 more
core +2 more sources
Development of a Step Counting Algorithm Using the Ambulatory Tibia Load Analysis System for Tibia Fracture Patients [PDF]
, 2018 Introduction: Ambulation can be used to monitor the healing of lower extremity fractures. However, the ambulatory behavior of tibia fracture patients remains unknown due to an inability to continuously quantify ambulation outside of the clinic.
Ackerman, Matt +7 more
core +2 more sources
Clinical and Translational Medicine, 2023 Background Approximately 10% of all bone fractures result in delayed fracture healing or non‐union; thus, the identification of biomarkers and prognostic factors is of great clinical interest. MicroRNAs (miRNAs) are known to be involved in the regulation
Franziska Lioba Breulmann +6 more
doaj +1 more source
Determination of strength and debonding energy of a glass-concrete interface for encapsulation-based self-healing concrete [PDF]
, 2017 This paper presents a combined experimental-numerical analysis to assess the strength and fracture toughness of a glass-concrete interface. This interface is present in encapsulation-based self-healing concrete.
De Belie, Nele +5 more
core +2 more sources
Near-Infrared Spectroscopy Allows for Monitoring of Bone Fracture Healing via Changes in Oxygenation
Journal of Functional BiomaterialsBone fractures are associated with hypoxia, but no longitudinal studies of perfusion measurements in human patients have been reported despite the clinical and research potential.
Cedric Nowicki, Bergita Ganse
doaj +1 more source
Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength [PDF]
, 2014 Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against bone
Apel +39 more
core +3 more sources
Frontiers in Digital HealthBackgroundGait can be continuously monitored via vertical ground reaction force (VGRF) and centre of pressure (COP) measurement with pressure-sensing insoles.
Elke Warmerdam +6 more
doaj +1 more source
Correlation of serum PTH level and fracture healing speed in elderly patients with hip fracture
Journal of Orthopaedic Surgery and Research, 2019 Purpose To access serum parathyroid hormone (PTH) level in elderly patients with hip fracture in relation to fracture healing outcomes. Methods This study included 90 elderly male patients with hip fracture and they were defined as the hip fracture group,
Zhao-Nan Ban +5 more
doaj +1 more source
Genetic polymorphisms of NOS2 and predisposition to fracture non-union: A case control study based on Han Chinese population. [PDF]
PLoS ONE, 2018 A non-union, especially atrophic non-unions, is a permanent failure of healing following a fracture and can be difficult to treat. Approximately 5-10% of fractures will result in a non-union during the healing process.
Wei Huang +5 more
doaj +1 more source