Results 21 to 30 of about 87,920 (235)

Muscle atrophy in polytraumatized patients – a longitudinal observational pilot study

Frontiers in Physiology
In polytraumatized patients, muscle atrophy appears more pronounced than in immobilized healthy study participants. However, rates and trajectories of the acute muscle atrophy and associated parameters have not been reported.
Danjana Teves, Torsten Pastor, Torsten Pastor, Tatjana Pastor, Bergita Ganse, Bergita Ganse, Bergita Ganse   +6 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Longitudinal weight and plantar pressure distribution while standing after tibial or malleolar fractures in patients with or without fracture union

Scientific Reports
Fracture healing is usually monitored by clinical impressions and radiographs. Objective and easy methods for assessing fracture healing without radiation would be beneficial. The aim of this study was to analyse whether weight and plantar pressure while
Elke Warmerdam, Sonja Baumgartner, Tim Pohlemann, Bergita Ganse   +3 more
doaj   +1 more source

New Parameters Based on Ground Reaction Forces for Monitoring Rehabilitation Following Tibial Fractures and Assessment of Heavily Altered Gait

Sensors
Instrumented insoles have created opportunities for patient monitoring via long-term recordings of ground reaction forces (GRFs). As the GRF curve is altered in patients after lower-extremity fracture, parameters defined on established curve landmarks ...
Christian Wolff, Elke Warmerdam, Tim Dahmen, Tim Pohlemann, Philipp Slusallek, Bergita Ganse   +5 more
doaj   +1 more source

Biomechanical Characteristics of Osteoporotic Fracture Healing in Ovariectomized Rats: A Systematic Review.

PLoS ONE, 2016
Biomechanical tests are widely used in animal studies on osteoporotic fracture healing. However, the biomechanical recovery process is still unknown, leading to difficulty in choosing time points for biomechanical tests and in correctly assessing ...
Lin Chen, Long Yang, Min Yao, Xue-Jun Cui, Chun-Chun Xue, Yong-Jun Wang, Bing Shu   +6 more
doaj   +1 more source

NPY and CGRP Inhibitor Influence on ERK Pathway and Macrophage Aggregation during Fracture Healing

Cellular Physiology and Biochemistry, 2017
Aim: The aims of this study are to investigate the effects of neurotransmitters NPY and CGRP on ERK signaling in fracture healing, and to identify the correlation between macrophage aggregation and fracture healing. Methods: Male Sprague-Dawley rats were
Peng Tang, Chunguang Duan, Zheng Wang, ChunMei Wang, Guolin Meng, Kaifeng Lin, Qian Yang, Zhi Yuan   +7 more
doaj   +1 more source

Is sonic Hedgehog involved in human fracture healing? --a prospective study on local and systemic concentrations of SHH. [PDF]

PLoS ONE, 2014
INTRODUCTION: Sonic Hedgehog (SHH) is a new signalling pathway in bone repair. Evidence exist that SHH pathway plays a significant role in vasculogenesis and limb development during embryogenesis.
Stefan Eipeldauer, Anita Thomas, Leonard Hoechtl-Lee, Mathias Kecht, Harald Binder, Julia Koettstorfer, Markus Gregori, Kambiz Sarahrudi   +7 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Long-term continuous instrumented insole-based gait analyses in daily life have advantages over longitudinal gait analyses in the lab to monitor healing of tibial fractures

Frontiers in Bioengineering and Biotechnology
Introduction: Monitoring changes in gait during rehabilitation allows early detection of complications. Laboratory-based gait analyses proved valuable for longitudinal monitoring of lower leg fracture healing.
Elke Warmerdam, Christian Wolff, Marcel Orth, Tim Pohlemann, Bergita Ganse, Bergita Ganse   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source