Results 21 to 30 of about 1,721,489 (338)
Stem cell research & therapeutics, 2020 As important players in cell-to-cell communication, exosomes (exo) are believed to play a similar role in promoting fracture healing. This study investigated whether exosomes derived from bone marrow mesenchymal stem cells (BMMSC-Exos) could improve ...
Lu Zhang +9 more
semanticscholar +1 more source
The biology of fracture healing [PDF]
Injury, 2011 The biology of fracture healing is a complex biological process that follows specific regenerative patterns and involves changes in the expression of several thousand genes. Although there is still much to be learned to fully comprehend the pathways of bone regeneration, the over-all pathways of both the anatomical and biochemical events have been ...
Richard Marsell, Thomas A. Einhorn
openaire +3 more sources
Journal of Nanobiotechnology, 2020 Transplantation of mesenchymal stem cells (MSCs) has been considered an effective therapeutic treatment for a variety of diseases including bone fracture. However, there are associated complications along with MSCs transplantation.
Tao Xu +9 more
semanticscholar +1 more source
Age‐related changes to macrophages are detrimental to fracture healing in mice
Aging Cell, 2020 The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age ...
D. Clark +8 more
semanticscholar +1 more source
Bone Healing and Inflammation: Principles of Fracture and Repair
Seminars in Plastic Surgery, 2021 Bones comprise a significant percentage of human weight and have important physiologic and structural roles. Bone remodeling occurs when healthy bone is renewed to maintain bone strength and maintain calcium and phosphate homeostasis. It proceeds through
Hassan Elhawary +5 more
semanticscholar +1 more source
Dynamization of the plate in treating nonunion of the tibial fracture: Case report
Journal of Orthopaedic Reports, 2023 Background: Plate osteosynthesis for the tibial fracture is one of the alternative treatments with satisfactory outcomes. Appropriate surgical techniques, including an open or minimally invasive approach, absolute or relative stability regarding fracture
Chittawee Jiamton +4 more
doaj +1 more source
Heterogeneity of murine periosteum progenitors involved in fracture healing
bioRxiv, 2020 The periosteum is the major source of cells involved in fracture healing. We sought to characterize progenitor cells and their contribution to bone fracture healing. The periosteum is highly enriched for progenitor cells, including Sca1+ cells, CFU-F and
B. Matthews +7 more
semanticscholar +1 more source
Research progress in the roles of Notch signaling pathway during fracture healing
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Fracture is the most common large-organ injury in humans. It takes several months or even longer from the onset to the completion of bone reconstruction. In severe cases, delayed healing or even bone discontinuity can occur.
GUO Liqiang, ZHAO Shitian, SHU Bing
doaj +1 more source
Immunohistochemical localization of key arachidonic acid metabolism enzymes during fracture healing in mice. [PDF]
PLoS ONE, 2014 This study investigated the localization of critical enzymes involved in arachidonic acid metabolism during the initial and regenerative phases of mouse femur fracture healing.
Hsuan-Ni Lin, J Patrick O'Connor
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Bone Reports, 2021 Introduction: Osteoporosis is characterised by low bone mass and micro-architectural deterioration of bone structure. Its treatment is directed at the processes of bone formation or resorption, that are of utmost importance in fracture healing.
E.A. Gorter +4 more
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