Results 61 to 70 of about 1,759,920 (268)
Computational Modeling of the Effects of Inflammatory Response and Granulation Tissue Properties on Human Bone Fracture Healing [PDF]
Bone healing process includes four phases: inflammatory response, soft callus formation, hard callus development, and remodeling. Mechanobiological models have been used to investigate the role of various mechanical and biological factors on the bone healing.
arxiv
On penalization in variational phase-field models of brittle fracture [PDF]
Irreversible evolution is one of the central concepts as well as implementation challenges of both the variational approach to fracture by Francfort and Marigo (1998) and its regularized counterpart by Bourdin, Francfort and Marigo (2000, 2007 and 2008), which is commonly referred to as a phase-field model of brittle fracture.
arxiv +1 more source
Accumulating evidence demonstrates that the Wnt/β-catenin signaling pathway plays a dominant role in bone repair. However, the role of Wnt/β-catenin signaling in the remodeling phase during bone fracture healing is currently unknown. In the present study,
Quanwei Bao+10 more
semanticscholar +1 more source
Biologic adjuvants for fracture healing [PDF]
Bone tissue has an exceptional quality to regenerate to native tissue in response to injury. However, the fracture repair process requires mechanical stability or a viable biological microenvironment or both to ensure successful healing to native tissue.
Mandeep S Virk, Jay R. Lieberman
openaire +2 more sources
Profiling microRNA expression during fracture healing
BackgroundThe discovery of microRNA (miRNA) has revealed a novel type of regulatory control for gene expression. Increasing evidence suggests that miRNA regulates chondrocyte, osteoblast, and osteoclast differentiation and function, indicating miRNA as ...
T. Waki+8 more
semanticscholar +1 more source
Nonlinear mechanics of thermoreversibly associating dendrimer glasses [PDF]
We model the mechanics of associating trivalent dendrimer network glasses with a focus on their energy dissipation properties. Various combinations of sticky bond (SB) strength and kinetics are employed. The toughness (work-to-fracture) of these systems displays a surprising deformation-protocol dependence; different association parameters optimize ...
arxiv +1 more source
Cyclical micromovement and fracture healing [PDF]
We studied 56 patients with fractures of the tibial shaft in a multicentre prospective randomised trial of three methods of external fixation. Group I was treated with a fixator which was unlocked at 4 to 6 weeks to allow free axial compression (axial dynamisation) with weight-bearing. Group II was treated with a fixator that was similarly unlocked at
Noordeen, M+4 more
openaire +4 more sources
Application of Salubrinal for Bone Fracture Healing [PDF]
The long-term objective of this project is to commercialize a novel synthetic chemical agent, salubrinal, for treatment of bone growth and fracture healing.
Lin, Chien-Chi, Yokota, Hiroki
core
The effect of whole body vibration on fracture healing - a systematic review.
This systematic review examines the efficacy and safety of whole body vibration (WBV) on fracture healing. A systematic literature search was conducted with relevant keywords in PubMed and Embase, independently, by two reviewers.
J. Wang, K. Leung, S. Chow, W. Cheung
semanticscholar +1 more source
Inroads Toward Robot-Assisted Internal Fixation of Bone Fractures Using a Bendable Medical Screw and the Curved Drilling Technique [PDF]
Internal fixation is a common orthopedic procedure in which a rigid screw is used to fix fragments of a fractured bone together and expedite the healing process. However, the rigidity of the screw, geometry of the fractured anatomy (e.g. femur and pelvis), and patient age can cause an array of complications during screw placement, such as improper ...
arxiv