Results 61 to 70 of about 1,759,920 (268)

Computational Modeling of the Effects of Inflammatory Response and Granulation Tissue Properties on Human Bone Fracture Healing [PDF]

open access: yesarXiv, 2018
Bone healing process includes four phases: inflammatory response, soft callus formation, hard callus development, and remodeling. Mechanobiological models have been used to investigate the role of various mechanical and biological factors on the bone healing.
arxiv  

On penalization in variational phase-field models of brittle fracture [PDF]

open access: yes, 2018
Irreversible evolution is one of the central concepts as well as implementation challenges of both the variational approach to fracture by Francfort and Marigo (1998) and its regularized counterpart by Bourdin, Francfort and Marigo (2000, 2007 and 2008), which is commonly referred to as a phase-field model of brittle fracture.
arxiv   +1 more source

An appropriate Wnt/β-catenin expression level during the remodeling phase is required for improved bone fracture healing in mice

open access: yesScientific Reports, 2017
Accumulating evidence demonstrates that the Wnt/β-catenin signaling pathway plays a dominant role in bone repair. However, the role of Wnt/β-catenin signaling in the remodeling phase during bone fracture healing is currently unknown. In the present study,
Quanwei Bao   +10 more
semanticscholar   +1 more source

Biologic adjuvants for fracture healing [PDF]

open access: yesArthritis Research & Therapy, 2012
Bone tissue has an exceptional quality to regenerate to native tissue in response to injury. However, the fracture repair process requires mechanical stability or a viable biological microenvironment or both to ensure successful healing to native tissue.
Mandeep S Virk, Jay R. Lieberman
openaire   +2 more sources

Profiling microRNA expression during fracture healing

open access: yesBMC Musculoskeletal Disorders, 2016
BackgroundThe discovery of microRNA (miRNA) has revealed a novel type of regulatory control for gene expression. Increasing evidence suggests that miRNA regulates chondrocyte, osteoblast, and osteoclast differentiation and function, indicating miRNA as ...
T. Waki   +8 more
semanticscholar   +1 more source

Nonlinear mechanics of thermoreversibly associating dendrimer glasses [PDF]

open access: yes, 2013
We model the mechanics of associating trivalent dendrimer network glasses with a focus on their energy dissipation properties. Various combinations of sticky bond (SB) strength and kinetics are employed. The toughness (work-to-fracture) of these systems displays a surprising deformation-protocol dependence; different association parameters optimize ...
arxiv   +1 more source

Cyclical micromovement and fracture healing [PDF]

open access: yesThe Journal of Bone and Joint Surgery. British volume, 1995
We studied 56 patients with fractures of the tibial shaft in a multicentre prospective randomised trial of three methods of external fixation. Group I was treated with a fixator which was unlocked at 4 to 6 weeks to allow free axial compression (axial dynamisation) with weight-bearing. Group II was treated with a fixator that was similarly unlocked at
Noordeen, M   +4 more
openaire   +4 more sources

Application of Salubrinal for Bone Fracture Healing [PDF]

open access: yes, 2014
The long-term objective of this project is to commercialize a novel synthetic chemical agent, salubrinal, for treatment of bone growth and fracture healing.
Lin, Chien-Chi, Yokota, Hiroki
core  

The effect of whole body vibration on fracture healing - a systematic review.

open access: yesEuropean Cells & Materials, 2017
This systematic review examines the efficacy and safety of whole body vibration (WBV) on fracture healing. A systematic literature search was conducted with relevant keywords in PubMed and Embase, independently, by two reviewers.
J. Wang, K. Leung, S. Chow, W. Cheung
semanticscholar   +1 more source

Inroads Toward Robot-Assisted Internal Fixation of Bone Fractures Using a Bendable Medical Screw and the Curved Drilling Technique [PDF]

open access: yesarXiv, 2018
Internal fixation is a common orthopedic procedure in which a rigid screw is used to fix fragments of a fractured bone together and expedite the healing process. However, the rigidity of the screw, geometry of the fractured anatomy (e.g. femur and pelvis), and patient age can cause an array of complications during screw placement, such as improper ...
arxiv  

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