Results 41 to 50 of about 409,065 (293)

Advances on creep–fatigue damage assessment in notched components [PDF]

open access: yes, 2017
In this paper, the extended Direct Steady Cyclic Analysis method (eDSCA) within the Linear Matching Method Framework (LMMF) is combined with the Stress Modified Ductility Exhaustion method and the modified Cavity Growth Factor (CGF) for the first time ...
Barbera, D., Chen, H., Liu, Y.
core   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Improving the cycle fatigue life of spring steel by a novel thermal cycling process

open access: yesMaterials Research Express, 2021
A novel thermal cycling process was applied on the 65Mn spring to improve the cycle fatigue life. Results demonstrate that the cycle fatigue life after the thermal cycling process was improved from 3 times to 14 times, with an improvement of 470%.
Wangyang Hu   +4 more
doaj   +1 more source

Design of fixed blast valve for gas extraction grouting sealing device

open access: yesMeikuang Anquan, 2021
Taking practice of gas extraction and sealing hole grouting in coal mine as background, a new type of blast valve was developed in view of the current situation that the existing blast valves can not meet the requirements of new grouting sealing device.
SUN Zhidong, MA Geng, SUN Yuning
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

FATIGUE FAILURE OF NICKEL-TITANIUM INSTRUMENTS IN ENDODONTICS AND ITS INFLUENCING FACTORS

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2022
Introduction and aim: The fracture of Ni-Ti instruments is a complication that most dentists will sooner or later encounter in the dental office. There are mainly two basic mechanisms behind it and these are exceeding the cyclic fatigue limit, exceeding ...
A Jusku   +6 more
doaj   +1 more source

Aggregate effect on the concrete cone capacity of an undercut anchor under quasi-static tensile load [PDF]

open access: yes, 2018
In the last decades, fastening systems have become an essential part of the construction industry. Post-installed mechanical anchors are frequently used in concrete members to connect them with other load bearing structural members, or to attach ...
Boumakis, Ioannis   +4 more
core   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Research progress of syntactic foams used in solid buoyance material

open access: yesCailiao gongcheng, 2022
Buoyant materials, as an important counterweight material of the deep-sea devices, play an important role in providing the equipment with enough buoyance as much as possible.
REN Sue, WANG Yana, YANG Cheng
doaj   +1 more source

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