Results 31 to 40 of about 155,276 (311)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Growth, History, or Institutions? What Explains State Fragility in Sub-Saharan Africa [PDF]
We explore the determinants of state fragility in sub-Saharan Africa. Controlling for a wide range of economic, demographic, geographic and istitutional regressors, we find that institutions, and in particular the civil liberties index and the number of ...
Graziella Bertocchi, Andrea Guerzoni
core +4 more sources
SPECIFIC STRUCTURE OF EFFECTIVE MEMBRANE ALLOYS BASED ON NIOBIUM, VANADIUM AND ZIRCONIUM
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2021 With unique mechanical and functional properties, amorphous, nanocrystalline and matrix duplex microstructure membrane alloys based on group V elements actively contribute to the development of hydrogen energy.
E.D. Kurbanova +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Per un umanesimo della fragilità. La fragilità come virtù politica [PDF]
Democrazia e Diritti Sociali, 2023 How did we come to lose fragility as a constitutive value in the formation of the human being, reducing it to little less than a character defect to be treated?
Carmela Bianco
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
CCL5 Induces a Sarcopenic-like Phenotype via the CCR5 Receptor
AntioxidantsSarcopenia corresponds to a decrease in muscle mass and strength. CCL5 is a new myokine whose expression, along with the CCR5 receptor, is increased in sarcopenic muscle.
Francisco Aguirre +14 more
doaj +1 more source
Fragilité, vulnérabilité et ressorts de santé des personnes âgées
Populations Vulnérables, 2017 À partir d’observations socio-ethnographiques à domicile, cet article explore les conditions d’application des notions de fragilité, vulnérabilité et atouts / ressorts de santé au repérage, au suivi et à la prévention de la perte d’autonomie des ...
Hervé Michel +4 more
doaj +1 more source