Results 41 to 50 of about 205,015 (256)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
OralMandibular osteoma is a benign bone tumour that is frequently discovered incidentally during a routine radiographic examination. Surgical management may be challenging when the lesion is located close to the inferior alveolar nerve, due to the potential ...
Maria Elena Mauceri +6 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
State fragility and economic vulnerability: what is measured and why? [PDF]
State fragility is a concept that emerged among the international community of donors in order to adapt aid policies to particularly difficult situations.
Sylviane GUILLAUMONT JEANNENEY +1 more
core +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The Fragility-Grievances-Conflict Triangle in the Middle East and North Africa (MENA)
, 2022 Several problems related to violence, grievances, and states’ lack of legitimacy and capacity to manage economic, social, and political issues are clustered together as an interactive structure in the Middle East and Northern Africa (MENA) region.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Gel and glass transition in fragile colloidal clays
Condensed Matter Physics, 2019 Dynamic Light Scattering (DLS) measurements were performed on colloidal suspensions of Laponite® at different concentrations in the range C_w = (1.5÷3.0)%.
R. Angelini, G. Ruocco, B. Ruzicka
doaj +1 more source
The role of Christianity in mending societal fragility and quelling violence in Liberia
Verbum et Ecclesia, 2017 This article has benefited from the research entitled The role of Christianity in post-war Liberia . It is a study that attempts to examine and investigate how Christian faith and spirituality can play a role in a campaign for social peace, justice ...
Eric Gbotoe, Selaelo T. Kgatla
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source