Results 51 to 60 of about 187,854 (309)

The Fragile Definition of State Fragility [PDF]

open access: yes, 2010
We investigate the link between fragility and economic development in sub-Saharan Africa over a yearly panel covering the 1999-2004 period. Beside the conventional definition of fragility adopted by the OECD Development Assistance Committee, we introduce the more severe definition of extreme fragility.
Bertocchi, G., Guerzoni, D.
openaire   +4 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Editorial for Special Issue “Exclusive Papers of the Editorial Board Members of Oral”

open access: yesOral
In 2022, the World Health Organization (WHO) released a landmark report on oral health, emphasizing the staggering global prevalence of oral disorders, which affect approximately 3 [...]
Giuseppina Campisi
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Animal Death and Religion: Revisiting Creaturely Vulnerability, Mourning and Sacrifice

open access: yesZoophilologica, 2019
Choć kwestia zwierzęcej śmierci i umierania od dawna zwraca uwagę badaczy z kręgu animal studies, coraz częstsze jej pojawianie się w obszarze studiów religioznawczych jest zjawiskiem interesującym i stosunkowo nowym, które domaga się rozważenia.
Alina Mitek-Dziemba
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

State fragility and economic vulnerability: what is measured and why? [PDF]

open access: yes
State fragility is a concept that emerged among the international community of donors in order to adapt aid policies to particularly difficult situations.
Sylviane GUILLAUMONT JEANNENEY   +1 more
core   +2 more sources

Promoting a bundle of biofortified seeds and agricultural inputs in northeastern Nigeria

open access: yes, 2023
Smallholder farmers in northeastern Nigeria face the triple threat of food insecurity, climate volatility, and conflict. Northeastern Nigeria has some of the highest levels of food insecurity in Nigeria.
Misra, Rewa; Amare, Mulubrhan; Ambler, Kate; Bamiwuye, Temilolu; Bloem, Jeffrey R.; Wagner, Julia   +1 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

« Faire connaissance avec la fragilité des choses »

open access: yesRevue d'anthropologie des connaissances
This text is a reflection on material fragilities, grounded in the discussion of two case studies, which look at the reclamation of red mud from bauxite mining in Gardanne and the management of sealed biological samples used in the production of DNA ...
Ashveen Peerbaye
doaj   +1 more source

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