Results 71 to 80 of about 187,854 (309)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

A model of financial fragility [PDF]

This paper presents a dynamic, stochastic game-theoretic model of financial fragility. The model has two essential features. First, interrelated portfolios and payment commitments forge financial linkages among agents.
Stacey L. Schreft, Roger D. Lagunoff
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Capturing the Invisible

Svetovi
This article explores how digital devices shape aesthetic perceptions and interactions with fragile Finnish mires. Through senso-digital walking interviews, it examines how technologies like mobile cameras, social media, and navigation apps influence ...
Kirsi Laurén, Tiina Seppä, Juhana Venäläinen   +2 more
doaj   +1 more source

The Fragile Consensus on Fragility

, 2010
The concept of fragility, which was initially born in the security arena, has been gaining increasing relevance in the development discourse over the past few years. However, fragility still remains a fuzzy and elusive term. This paper identifies three main sets of definitions of fragility, which substantially differ in their focus and breadth.
BERTOLI, Simone, TICCI, Elisa
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Big Data for the stratification of readmission risk after hospital discharge of older adults with complex conditions

International Journal of Integrated Care, 2019
Introduction and objective: The increase in life expectancy along with scientific advances have led to an increasing number of elderly patients with several chronic conditions, requiring frequent hospital admissions due to exacerbation of their chronic ...
Xue He, Neus Gual, Ricard Gavaldà, Marco Inzitari   +3 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Rethinking food crisis responses: The Nigeria presentation of IFPRI's 2023 Global Food Policy Report & the launch of the CGIAR Research Initiative on Fragility, Conflict & Migration (FCM)

, 2023
The purpose of this report is to describe work presented and discussions resulting from an event jointly convened by the CGIAR Research Initiative on Fragility, Conflict, and Migration (FCM) and the International Food Policy Research Institute (IFPRI) in
https://orcid.org/0000-0001-9906-0107 Carrillo, Lucia; http://orcid.org/0000-0002-5126-5215 Kosec, Katrina; http://orcid.org/0000-0001-6035-1732 Smart, Jennifer; http://orcid.org/0000-0001-6277-0930 Ambler, Kate; http://orcid.org/0000-0002-4138-1693 Andam, K.; http://orcid.org/0000-0003-0560-3604 Edeh, Hyacinth O.; https://orcid.org/0000-0001-8259-7186 Fasoranti, Adetunji, Carrillo, Lucia; Kosec, Katrina; Onilogbo, Omobolanle; Smart, Jenny; Ambler, Kate; Andam, Kwaw S.; Anisimova, Evgeniya; Edeh, Hyacinth; Fasoranti, Adetunji; Mugisho, Aline   +1 more
core   +1 more source