Results 71 to 80 of about 2,232,356 (345)
THE DISTRIBUTION CURVE OF ERYTHROCYTE FRAGILITY [PDF]
Blood, 1949 Abstract 1. A simple method of representing erythrocyte fragility as a distribution curve of actual cellular fragility is described. 2. The importance of deciding the form of a distribution before using summarizing statistics is emphasized. 3.
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Robustness of the European power grids under intentional attack [PDF]
, 2007 The power grid defines one of the most important technological networks of our times and sustains our complex society. It has evolved for more than a century into an extremely huge and seemingly robust and well understood system. But it becomes extremely
B. A. Carreras +10 more
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
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Plasticization and antiplasticization of polymer melts diluted by low molar mass species
, 2010 An analysis of glass formation for polymer melts that are diluted by structured molecular additives is derived by using the generalized entropy theory, which involves a combination of the Adam-Gibbs model and the direct computation of the configurational
DiMarzio E. A. +10 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Japan Architectural Review, 2019 The Sosokan building of Keio University located in Yokohama, Japan, is a base‐isolated building with a semi‐active control system. The semi‐active dampers’ damping coefficient is changed to best reproduce the optimal control force in linear‐quadratic ...
Masayuki Kohiyama +4 more
doaj +1 more source
Empirical fragility curves for Peruvian school buildings [PDF]
WIT Transactions on The Built Environment, Vol 93, 2007 This paper describes an estimation of economic losses in Peruvian educational buildings for different levels of seismic action. Opinions of experts were processed to generate seismic intensity versus damage relationships. Economic losses were then expressed through fragility curves and damage matrices. For frequent earthquakes (50-year return period) a
A. Muñoz +3 more
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Seismic Risk Analysis of Revenue Losses, Gross Regional Product and transportation systems. [PDF]
, 2013 Natural threats like earthquakes, hurricanes or tsunamis have shown seri- ous impacts on communities. In the past, major earthquakes in the United States like Loma Prieta 1989, Northridge 1994, or recent events in Italy like L’Aquila 2009 or Emilia 2012 ...
Carturan, Federico
core
The fragility of planetary systems [PDF]
, 2015 We specify the range to which perturbations penetrate a planetesimal system. Such perturbations can originate from massive planets or from encounters with other stars.
Jilkova, Lucie, Zwart, Simon Portegies
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
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