Results 91 to 100 of about 685,305 (257)

Research Brief: Generating Building-specific Fragility Curves

, 2019
Fragility curves represent a structure’s likelihood of damage under a range of load levels—like those from natural hazards. They, therefore, help to set building code safety factors, resiliency ratings, and even insurance premiums.
Pellenq, Roland, Mulla, Talal, Ulm, Franz-Josef   +2 more
core  

Seismic fragility curves for soft-storey buildings

, 2006
Buildings with a soft-storey are notoriously vulnerable to collapse under strong earthquake shaking. However, a building subject to a small or moderate magnitude earthquake has a fair chance of survival depending on the drift demand on the softstorey ...
John Wilson (18926458), Kittipoom Rodsin (19117423), Helen Goldsworthy (18999566), Nelson T. K. Lam (19008725)   +3 more
core   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Growth, History, or Institutions? What Explains State Fragility in Sub-Saharan Africa [PDF]

We explore the determinants of state fragility in sub-Saharan Africa. Controlling for a wide range of economic, demographic, geographic and istitutional regressors, we find that institutions, and in particular the civil liberties index and the number of ...
Graziella Bertocchi, Andrea Guerzoni
core   +2 more sources

Comparing the performance of retrofitting strategies in URM buildings through fragility curves

Recent earthquakes have highlighted the seismic vulnerability of existing masonry buildings, pointing out the urgent need to design high-performant and non-invasive strengthening interventions.
Sergio Lagomarsino, Stefania Degli Abbati, Andrea Brunelli, Arash Rooshenas   +3 more
core   +1 more source

Multidimensional seismic fragility analysis of subway station structures using the adaptive bandwidth kernel density estimation and Copula function

Underground Space
Structural damages during an earthquake are typically controlled by seismic demands, which are represented by the combination of amplitude of ground motion and cyclic load effects.
Chunyi Cui, Jingtong Zhao, Minze Xu, Chengshun Xu, Hailong Liu, Kunpeng Wang   +5 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

FRAGILITY CURVES ANALYTIC FOR SEISMIC EVALUATION OF CABLE-STAYED BRIDGE [PDF]

, 2020
. This study presented the convenient method to develop the fragility curves in probability of damage exceedance and intensity relation of the cablestayed bridge.
ade, prayoga nasution
core   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Seismic Fragility Estimation Based on Machine Learning and Particle Swarm Optimization

Buildings
In seismic performance assessment, the development of building fragility curves is critical for performance-based engineering. Traditional methods for time history analysis, reliant on detailed ground motion (GM) inputs, often suffer from inefficiency ...
Qingzhao Kong, Jiaxuan Liu, Xiaohan Wu, Cheng Yuan   +3 more
doaj   +1 more source