Results 81 to 90 of about 16,975 (302)
Probabilistic seismic slope stability assessment of geostructures
, 2010 Summarization: Typically, seismic analysis of large-scale geostructures, such as embankments, is performed by means of deterministic pseudostatic slope stability methods, where a safety factor based approach is adopted.
Georgopoulos, EC +7 more
core +1 more source
DEVELOPMENT OF FRAGILITY CURVES FOR REINFORCED DUNES
Coastal Engineering Proceedings, 2018 The objective of this paper is to present the results of on-going field studies to assess the performance of geotextile sand-filled container (GSC) reinforced dunes and to develop probabilistic fragility curves for a range of damage states to these structures.
Maggi, Brian +6 more
openaire +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
MATEC Web of Conferences, 2019 Fragility curves express the seismic vulnerability of bridge piers for different damage states at various earthquake intensities. A fragility curve typically gives a physical understanding of repair costs and functionally levels of a bridge pier.
Ahmad Nursafarina +2 more
doaj +1 more source
A new methodology of the development of seismic fragility curves
, 2014 There are continuous efforts to mitigate structural losses from earthquakes and manage risk through seismic risk assessment; seismic fragility curves are widely accepted as an essential tool of such efforts.
Lee, Young Joo, Moon, Dosoo
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Applied Sciences, 2020 Fragility curves are essential tools to quantitatively assess the physical vulnerability of structures and infrastructures at risk for a given seismic hazard.
Angelo Anelli, Federico Mori, Marco Vona
doaj +1 more source
Fragility Curves of Restoration Processes for Resilience Analysis [PDF]
, 2017 In literature the fragility curves are usually adopted to evaluate the probability of exceedance of a given damage state. This chapter presents for the first time a procedure for developing fragility curves of restoration processes which can be adopted for resilience analysis.
openaire +2 more sources
Seismic Fragility Assessment of Hiraya Building Using Fragility Curves
Seismic Fragility Assessment of Hiraya Building Using Fragility CurvesThe Hiraya Building, a three-story educational facility at Caraga State University-Main Campus in Ampayon, Butuan City, Agusan del Norte, Caraga Region, is situated near the Surigao segment of the Philippine Fault, making it highly susceptible to seismic activity due to the country's location within the Pacific Ring of Fire.
null Sicenio D. Abera Jr. +3 more
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source