Results 61 to 70 of about 16,975 (302)

Seismic assessment of a multi-span steel railway bridge in Turkey based on nonlinear time history [PDF]

Natural Hazards and Earth System Sciences, 2018
Many research studies have shown that bridges are vulnerable to earthquakes, graphically confirmed by incidents such as the San Fernando (1971 USA), Northridge (1994 USA), Great Hanshin (1995 Japan), and Chi-Chi (1999 Taiwan) earthquakes, amongst many
M. F. Yılmaz, M. F. Yılmaz, B. Ö. Çağlayan   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

First-order approximation towards empirical seismic vulnerability assessment of low-cost unreinforced masonry buildings in South Africa

Geomatics, Natural Hazards & Risk
The 5 August 2014 Orkney earthquake in South Africa caused significant damage to low-cost unreinforced masonry buildings. After the earthquake, post-earthquake surveys were conducted to assess damage and deduce the intensity experienced by these ...
Thando Nqasha, Zeenat Khoyratty, Mulemwa Akombelwa, Mayshree Singh, Andrzej Kijko   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Seismic fragility analysis of subway station structures considering statistical uncertainty of seismic demands

Yantu gongcheng xuebao
To avoid the epistemic uncertainty for seismic fragility of subway station structures caused by the incomplete seismic demand sample set, a novel procedure of seismic fragility analysis of subway station structures considering the statistical uncertainty
CUI Chunyi 1 , XU Minze 1, XU Chengshun 2, ZHAO Jingtong 1, LIU Hailong 1, MENG Kun 3
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Seismic performance assessment of subway station structures considering fuzzy probability of damage states

Yantu gongcheng xuebao, 2022
Quantification of structural damage states in the fragility analysis and seismic performance evaluation of underground structures usually adopts the deterministic threshold values, which is a limitation in the framework of performance-based seismic ...
ZHONG Zi-lan , SHI Yue-bo , LI Jin-qiang , ZHAO Mi , DU Xiu-li
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Seismic fragility curves for the European building stock: review and evaluation of existing fragility curves

, 2015
Earthquakes continue to represent a serious threat for some European countries, particularly for Mediterranean bordering countries, where these events have been triggering significant destruction and loss over the last decades.
SIMOES DIAS MAIO Rui, TSIONIS Georgios
core   +1 more source