Results 51 to 60 of about 685,305 (257)

Analytical fragility curves for assessment of the seismic vulnerability of HP/HT unburied subsea pipelines

open access: yes, 2020
Vulnerability of subsea high pressure/high temperature (HP/HT) pipelines to seismic actions is studied numerically. Unlike most of the existing researches on buried or trenched pipelines, this study is focused on the response of an unburied pipeline with
Mina, Daniele   +2 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Machine Learning-based Seismic Fragility Curves for RC Bridge Piers [PDF]

open access: yes, 2022
A significant part of ongoing studies in the field of earthquake engineering is directed toward the seismic risk assessment of buildings and infrastructures at a territorial scale.
Monti G.   +4 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Fragility curves for buildings in Hong Kong [PDF]

open access: yes, 2019
Fragility curves are the tools for evaluating the damage of structural or nonstructural components under different levels of ground excitation. It is also the necessary information for calculating the life-cycle cost of buildings during their design ...
Wong, Ho-Fai, Luk, Sung-Hei
core   +2 more sources

Fragility curves for hardfill dams under seismic loading / Curvas de fragilidad para presas de hardfill bajo carga sísmica

open access: yesTecnología y ciencias del agua, 2020
Hardfill dams are comprised of cemented granular materials gathered directly from the river bed or its surroundings, or which are by-product of the dam excavation.
Grissel Hurtado-López   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Seismic risk analysis of multistory reinforced concrete structures in Saudi Arabia

open access: yesCase Studies in Construction Materials, 2018
In this research, analytical fragility curves for typical mid-rise plane reinforced concrete moment-resisting frames in Kingdom of Saudi Arabia, KSA, which is considered low-seismicity area, are presented.
Yasser E. Ibrahim
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Analytical Seismic Fragility Curves for Reinforced Concrete Wall pier using Shape Memory Alloys considering maximum drift

open access: yesMATEC Web of Conferences, 2019
Fragility curves express the seismic vulnerability of bridge piers for different damage states at various earthquake intensities. A fragility curve typically gives a physical understanding of repair costs and functionally levels of a bridge pier.
Ahmad Nursafarina   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy