Results 101 to 110 of about 2,213,618 (351)
Applied SciencesSeismic fragility curves, derived from ground motion data, are essential tools for predicting and assessing potential damage to structures during earthquakes.
Sangki Park +3 more
doaj +1 more source
Force dependent fragility in RNA hairpins [PDF]
, 2006 We apply Kramers theory to investigate the dissociation of multiple bonds under mechanical force and interpret experimental results for the unfolding/refolding force distributions of an RNA hairpin pulled at different loading rates using laser tweezers ...
C. Bustamante +9 more
core +2 more sources
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Mainshock-Integrated Aftershock Vulnerability Assessment of Bridge Structures
Applied Sciences, 2020 Seismic fragility analysis is often conducted to quantify the vulnerability of civil structures under earthquake excitation. In recent years, besides mainshocks, strong aftershocks have been often witnessed to induce structural damage to engineered ...
Xuan Guo, Zheyu Zhang, ZhiQiang Chen
doaj +1 more source
A framework for probabilistic seismic risk assessment of NG distribution networks [PDF]
, 2016 Lifelines are essential infrastructures for human activities and the economic developm ent of a region. Lifelines vulnerability reduction is an actual question, particularly with reference to NaTech events, like earthquakes.
Faleschini, Flora +4 more
core +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Relaxation and physical aging in network glasses: a review
, 2016 Recent progresses in the description of glassy relaxation and ageing are reviewed for the wide class of network-forming materials such as $GeO_2$, Ge$_x$Se$_{1-x}$, silicates (SiO$_2$-Na$_2$O) or borates (B$_2$O$_3$-Li$_2$O), all of them having an ...
Micoulaut, M.
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source