Results 51 to 60 of about 1,379,022 (300)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Un juego serio en que se va la vida. Fragmentos, citas, reescrituras en Zettel, de Héctor Libertella

open access: yesPerífrasis. Revista de Literatura, Teoría y Crítica, 2015
Los papeles sueltos de Zettel, último libro Héctor Libertella, tienen algo de la tarea obstinada que Antoine Compagnon encuentra en niños y ancianos, trabajo del papel como cortar y pegar, juego serio en que se va la vida, o llega.
Agustina Pérez
doaj  

« Words came to the surface » : la résurgence comme remémoration de fragments poétiques dans Between the Acts de Virginia Woolf

open access: yesÉtudes Britanniques Contemporaines, 2009
In Between the Acts, remembering includes fleeting memories of poetic fragments ranging from romantic poems to nursery rhymes which are re-membered by the chorus of the pageant and Miss La Trobe.
Audrey Sabathier-Lepêtre
doaj   +1 more source

La vida y el fragmento

open access: yesCuadernos LIRICO, 2021
This essay attempts to unfold the possible relations between life and writing on the basis of some authors who, in narratives of varying lengths, reflect on this unsolvable tension.
Silvio Mattoni
doaj   +1 more source

Fragment-Based Excited-State Calculations Using the GW Approximation and the BetheSalpeter Equation

open access: yes, 2021
Herein, we present a fragment-based approach for calculating the charged and neutral excited states in molecular systems, based on the many-body Green’s function method within the GW approximation and the Bethe–Salpeter equation (BSE). The implementation
Yoshifumi Noguchi (1619881)   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors

open access: yes, 2019
Genome-wide-association studies in chronic low back pain patients identified sepiapterin reductase as a high interest target for developing new analgesics.
Markus Schade (194080)   +8 more
core   +2 more sources

« Getting back to tough eternal verities » ? Cyril Connolly et la pensée du fragment dans The Unquiet Grave

open access: yesÉtudes Britanniques Contemporaines, 2010
The Unquiet Grave is the “major” work of a “minor” author who is mostly remembered as editor of Horizon in the 1940s. Defying all attempts at classification, the book derives from an aesthetics of the fragmentary, with the first three parts consisting of
Jean-Christophe Murat
doaj   +1 more source

Àlvaro Siza and the Fragmented City [PDF]

open access: yesAthens Journal of Architecture, 2015
In Álvaro Siza’s work, between 1970 and 1980, the presence of the ruin results from his quest for a methodology that allows the inclusion of the city’s past and its remains as an important starting point to embrace reality in its broadest sense.
Carlos Machado
doaj   +1 more source

Fragment-Based Identification of Influenza Endonuclease Inhibitors [PDF]

open access: yes, 2016
The influenza virus is responsible for millions of cases of severe illness annually. Yearly variance in the effectiveness of vaccination, coupled with emerging drug resistance, necessitates the development of new drugs to treat influenza infections.
Credille, Cy V   +8 more
core   +1 more source

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