Results 171 to 180 of about 8,345 (257)

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

Ocular Half-Life: What it Does and Does Not Mean for Intravitreal Anti-angiogenic Drug Durability. [PDF]

Ophthalmol Ther
Avery R, Diack C, Holekamp N, Lhor M, Mar F, Maass K.   +5 more
europepmc   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

BMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim, Hak Yong Kim, Ja Hoon Koo, Gi Doo Cha, Dae‐Hyeong Kim, Hye Jin Kim   +5 more
wiley   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement-dependent cytotoxicity. [PDF]

FEBS J
Pinto AJ, Chouquet A, Bally I, Rossi V, Thielens NM, Dumestre-Pérard C, Kunert R, Gaboriaud C, Ling WL, Reiser JB.   +9 more
europepmc   +1 more source

Targeting a Dynamic Protein-Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex [PDF]

, 2015
Cota, E, Douse, CH, Tate, EW, Vrielink, N, Zhang, W   +4 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Elucidating the Interplay Between Structure and Electrochemical Behavior in Lignin‐Based Polymer Electrolytes for Potassium Batteries

Battery Energy, Volume 4, Issue 2, March 2025.
Three biobased membranes are synthesized by crosslinking oxidized Kraft lignin with poly(ethylene glycol) diglycidyl ether of increasing molecular weights. After incorporation of solvated potassium salts, potassium batteries including these biobased gel polymer electrolytes are able to deliver a maximum specific capacity at 0.05 A g−1 as high as 130 ...
Giuseppe Pascuzzi, Sabrina Trano, Carlotta Francia, Stefano Turri, Federico Bella, Gianmarco Griffini   +5 more
wiley   +1 more source

A Prototype timsOmni Platform Enables Confident Annotation of the Key Hypervariable CDR3 Regions of IgG Immunoglobulins Using Low- and High-Energy Electron-Based Fragmentation. [PDF]

Anal Chem
Ollivier S, Schuster D, van Rijswijck DMH, Stroganova I, Smyrnakis A, Fiala J, Kosmopoulou M, Suckau D, Pengelley S, Raether O, Greisch JF, Papanastasiou D, Heck AJR.   +12 more
europepmc   +1 more source

Consumer Adoption of Internet of Things

Journal of Consumer Behaviour, Volume 24, Issue 2, Page 673-693, March 2025.
ABSTRACT The Internet of Things (IoT), a pivotal technology in enhancing user connectivity, faces a paradox: its widespread potential yet limited consumer adoption. This study addresses this dichotomy by synthesizing a large‐scale meta‐analytic structural equation modeling (MASEM) and hierarchical linear meta‐analysis (HiLMA) of 2736 effect sizes from ...
Wagner Junior Ladeira, Weng Marc Lim, Fernando de Oliveira Santini, Tareq Rasul, Bernardo Frantz, Jean Carlos de Oliveira Rosa, Mohd Azhar   +6 more
wiley   +1 more source

Fc-Binding Cyclopeptide Induces Allostery from Fc to Fab: Revealed Through in Silico Structural Analysis to Anti-Phenobarbital Antibody. [PDF]

Foods
Zhou T, Zhang H, Yu X, Pan K, Yao X, Shen X, Lei H.   +6 more
europepmc   +1 more source