Results 1 to 10 of about 264,721 (290)

Baseline Frailty Measured by the Risk Analysis Index and 30-Day Mortality After Surgery for Spinal Malignancy: Analysis of a Prospective Registry (2011–2020) [PDF]

Neurospine
Objective To evaluate the prognostic utility of baseline frailty, measured by the Risk Analysis Index (RAI), for prediction of postoperative mortality among patients with spinal malignancy (SM) undergoing resection.
Rachel Thommen, Christian A. Bowers, Aaron C. Segura, Joanna M. Roy, Meic H. Schmidt   +4 more
doaj   +1 more source

Patterns of High-Dose and Long-Term Proton Pump Inhibitor Use: A Cross-Sectional Study in Six South Australian Residential Aged Care Services

Drugs - Real World Outcomes, 2019
Aim While proton pump inhibitors (PPIs) are generally considered safe and well tolerated, frail older people who take PPIs long term may be susceptible to adverse events.
Ivanka Hendrix, Amy T. Page, Maarit J. Korhonen, J. Simon Bell, Edwin C. K. Tan, Renuka Visvanathan, Tina Cooper, Leonie Robson, Janet K. Sluggett   +8 more
doaj   +1 more source

Evaluation of muscle quality and quantity for the assessment of sarcopenia using mid-thigh computed tomography: a cohort study

BMC Geriatrics, 2021
Background For the diagnosis of Sarcopenia, European Working Group on Sarcopenia in Older People (EWGSOP) revised the algorisms in 2019, where they added computed tomography (CT) as an assessment tool not only for quantity but also for quality in ...
Hiroki Oba, Yasumoto Matsui, Hidenori Arai, Tsuyoshi Watanabe, Hiroki Iida, Takafumi Mizuno, Satoshi Yamashita, Shinya Ishizuka, Yasuo Suzuki, Hideki Hiraiwa, Shiro Imagama   +10 more
doaj   +1 more source

Oxidative Stress and Cognitive Alterations Induced by Cancer Chemotherapy Drugs: A Scoping Review

Antioxidants, 2021
Cognitive impairment is one of the most deleterious effects of chemotherapy treatment in cancer patients, and this problem sometimes remains even after chemotherapy ends.
Omar Cauli
doaj   +1 more source

Prospective application of the risk analysis index to measure preoperative frailty in spinal tumor surgery: A single center outcomes analysis

World Neurosurgery: X, 2023
Introduction: Surgeons are frequently faced with challenging clinical dilemmas evaluating whether the benefits of surgery outweigh the substantial risks routinely encountered with spinal tumor surgery. The Clinical Risk Analysis Index (RAI-C) is a robust
Remy L. Link, Kavelin Rumalla, Evan N. Courville, Joanna M. Roy, Syed Faraz Kazim, Christian A. Bowers, Meic H. Schmidt   +6 more
doaj   +1 more source

Relative sit-to-stand power cut-off points and their association with negatives outcomes in older adults

Scientific Reports, 2021
The purposes of this study were: (i) to evaluate the association of sit-to-stand (STS) power and body composition parameters [body mass index (BMI) and legs skeletal muscle index (SMI)] with age; (ii) to provide cut-off points for low relative STS power (
Ivan Baltasar-Fernandez, Julian Alcazar, Asier Mañas, Luis M. Alegre, Ana Alfaro-Acha, Leocadio Rodriguez-Mañas, Ignacio Ara, Francisco J. García-García, Jose Losa-Reyna   +8 more
doaj   +1 more source

Rapid increase in departmental scholarly activity independent of residents demonstrates reproducibility and success of intensive research initiative in neurosurgery department

World Neurosurgery: X
Background: Neurological surgery remains one of the most competitive specialties with a match rate of
Samantha Varela, Meic H. Schmidt, Christian A. Bowers   +2 more
doaj   +1 more source

A Novel Bead-Based Immunoassay for the Measurement of Heat Shock Proteins 27 and 70

Pathogens, 2020
Heat shock proteins (HSPs) play an essential role in protecting proteins from denaturation and are implicated in diverse pathophysiological conditions like cardiovascular diseases, cancer, infections, and neurodegenerative diseases.
Rose Njemini, Katrijn Verhaeghen, Tony Mets, Ilse Weets, Ivan Bautmans   +4 more
doaj   +1 more source

Proceedings of the Canadian Frailty Network Summit: Medication Optimization for Frail Older Canadians, Toronto, Monday April 24, 2017

Canadian Geriatrics Journal, 2017
Appropriate and optimal use of medication and polypharmacy are especially relevant to the care of older Canadians living with frailty, often impacting their health outcomes and quality of life.
John Muscedere, Perry Kim, Peter Aitken, Michael Gaucher, Robin Osborn, Barbara Farrell, Jayna Holroyd-Leduc, Laurie Mallery, Henry Siu, James Downar, Todd C. Lee, Emily McDonald, Lisa Burry   +12 more
doaj   +1 more source

Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging

Journal of Cachexia, Sarcopenia and Muscle, 2020
Background Physical activity (PA) is a recognized contributor to healthy aging. However, the majority of studies exploring its associations with adverse outcomes in cohorts of older adults use single‐time PA estimates, which do not consider its dynamic ...
Juan Luis Sanchez‐Sanchez, Mikel Izquierdo, Jose Antonio Carnicero‐Carreño, Fransico José García‐García, Leocadio Rodríguez‐Mañas   +4 more
doaj   +1 more source