Results 91 to 100 of about 180,045 (314)

Associations of Frailty With the Risk of Incident Cancer and Cancer‐Related Mortality in Veterans With Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective This study investigated the association between frailty and cancer incidence and mortality in patients with rheumatoid arthritis (RA). It aimed to identify how frailty influences cancer risk and cancer‐specific outcomes. Methods This retrospective cohort study analyzed data from the Veterans’ Affairs Rheumatoid Arthritis Registry (2002–2023).
Bhavik Bansal, Aaron Baraff, Katherine Wysham, James S. Andrews, Bryant R. England, Ted R. Mikuls, Joshua Baker, Kaleb Michaud, Alexa Meara, Una Makris, Carolyn Presley, Ariela Orkaby, Namrata Singh   +12 more
wiley   +1 more source

Proportional hazards models with discrete frailty

We extend proportional hazards frailty models for lifetime data to allow a negative bi-nomial, Poisson, Geometric or other discrete distribution of the frailty variable. This might represent, for example, the unknown number of flaws in an item under test.
Crowder, Martin, Caroni, Chrys, Kimber, Alan   +2 more
core   +1 more source

Blood pressure variability and frailty in end-stage kidney disease [PDF]

Tom Mercer - ORCID: 0000-0002-5078-4769 https://orcid.org/0000-0002-5078-4769Marietta van der Linden - ORCID: 0000-0003-2256-6673 https://orcid.org/0000-0003-2256-6673Background High blood pressure variability (BPV) is a predictor of cardiovascular ...
Mercer, Tom, van der Linden, Marietta, Zanotto, Tobia, Koufaki, Pelagia   +3 more
core   +1 more source

PROCESS OF PHYSICAL DISABILITY AMONG OLDER ADULTS : CONTRIBUTION OF FRAILTY IN THE SUPER-AGED SOCIETY [PDF]

, 2012
2012-02One of the critical issues that Japan, well known for the world’s highest proportion of older adults, a super-aged society, is currently confronting is how to prevent physical disability in old age.
KUZUYA, MASAFUMI
core   +1 more source

Freeze‐Thaw Engineered Dual Conductivity Polymeric Binder Stabilizes Large‐Volume‐Change Lithium–Ion Battery Anodes

Advanced Functional Materials, EarlyView.
This work developed an all‐aqueous freeze‐thaw strategy to create a dual‐conductive PVA/P3KBT binder for high volume‐change lithium–ion battery anodes. The resulting binder system strengthens the electrode structure, supports ion and electron transport, and accommodates repeated volume changes, reducing cracking and improving long‐term cycling ...
Haoze Ren, Jeremy Wang, Han Li, Marie Francoise C. Millares, Hao Guo, Sz‐Chian Liou, Siyu Qin, Ryan Thorpe, Melissa A. Guercio, Dali Yang, Lu Ma, Siyu Wu, Ruipeng Li, Esther S. Takeuchi, Amy C. Marschilok, Shan Yan, Kenneth J. Takeuchi, Elsa Reichmanis   +17 more
wiley   +1 more source

Inflammation-Related Genes Are Differentially Expressed in Lipopolysaccharide-Stimulated Peripheral Blood Mononuclear Cells after 3 Months of Resistance Training in Older Women

Cells
Recently, we showed that three months of resistance exercise significantly alters 18 canonical pathways related to chronic inflammation in PBMCs of older adults.
Lene Salimans, Keliane Liberman, Wilfried Cools, Rose Njemini, Florence Debacq-Chainiaux, Louis Nuvagah Forti, Liza De Dobbeleer, Ron Kooijman, Ingo Beyer, Ivan Bautmans   +9 more
doaj   +1 more source

Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging

Journal of Cachexia, Sarcopenia and Muscle, 2020
Background Physical activity (PA) is a recognized contributor to healthy aging. However, the majority of studies exploring its associations with adverse outcomes in cohorts of older adults use single‐time PA estimates, which do not consider its dynamic ...
Juan Luis Sanchez‐Sanchez, Mikel Izquierdo, Jose Antonio Carnicero‐Carreño, Fransico José García‐García, Leocadio Rodríguez‐Mañas   +4 more
doaj   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Effectiveness of the Sub-Acute Care for Frail Elderly (SAFE) Transitional Care Unit on Short-Term Functional Independence in Frail Older Patients Discharged from Hospital

Canadian Geriatrics Journal
Background Transitional care programs help improve continuity of care and post-discharge outcomes for frail older adults who are hospitalized. In this study, we examined the effectiveness of a transitional care model, based in a long-term care (LTC ...
Benoît Robert, Annie H. Sun, Danielle Sinden, Anan B. Eddeen, Maya Murmann, Amy T. Hsu   +5 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source