Results 71 to 80 of about 180,045 (314)

A Novel Bead-Based Immunoassay for the Measurement of Heat Shock Proteins 27 and 70

Pathogens, 2020
Heat shock proteins (HSPs) play an essential role in protecting proteins from denaturation and are implicated in diverse pathophysiological conditions like cardiovascular diseases, cancer, infections, and neurodegenerative diseases.
Rose Njemini, Katrijn Verhaeghen, Tony Mets, Ilse Weets, Ivan Bautmans   +4 more
doaj   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Parametric frailty and shared frailty survival models [PDF]

Frailty models are the survival data analog to regression models, which account for heterogeneity and random effects. A frailty is a latent multiplicative effect on the hazard function and is assumed to have unit mean and variance theta, which is ...
Roberto G. Gutierrez
core  

Comparing frailty prevalence between countries: validation of the Global Burden of Disease study Frailty Index (GBD-FI) in the survey of health, ageing and retirement in Europe

, 2023
BACKGROUND: Accurate comparable prevalence proportions are required to better understand the epidemiology of frailty. Estimates in many countries are missing or incomparable.
B. Devleesschauwer, R. O\u27Caoimh, Kabir, Zubair, Sezgin, Duygu, D. Sezgin, Liew, Aaron, Devleesschauwer, Brecht, O’Donovan, Mark R., Z. Kabir, A. Liew, M.R. O\u27Donovan, O’Caoimh, Rónán, O’Donovan, Mark R   +12 more
core   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey, Jessica Fitzpatrick, Maria Dall'Era, Charmayne Dunlop‐Thomas, Courtney Hoge, S. Sam Lim, Patricia P. Katz, Jinoos Yazdany, Laura C. Plantinga   +8 more
wiley   +1 more source

Barriers and facilitators to prehabilitation participation among older adults undergoing major elective surgery: a qualitative study using the capability, opportunity, motivation - behavior model

BMC Geriatrics
Background Prehabilitation may improve patients’ functional capacity before surgery and enhance postoperative recovery. This study aimed to identify facilitators and barriers to participation in a multi-component prehabilitation program among older ...
Kuan-Yuan Wang, Christine Y. Nguyen, Kailin Xu, Yuchen Liu, Natalie Newmeyer, Sussan Alshanniek, Jennifer A. Palmer, Dae Hyun Kim   +7 more
doaj   +1 more source

Frailty in survival analysis models (parametric frailty, parametric shared frailty, and frailty in Cox models [PDF]

Frailty models are used to model survival times in the presence of overdispersion or group-specific random effects. The latter are distinguished from the former by the term "shared" frailty models.
Roberto G. Gutierrez
core  

Longitudinal Measurements of FGF23, Sarcopenia, Frailty and Fracture in Older Community Dwelling Women [Elektronisk resurs]

, 2023
Background: FGF23 has been associated with frailty and functional performance in older individuals, but the association to sarcopenia is unknown. Objectives: To investigate the association between FGF23, frailty, sarcopenia and fractures in older ...
Paulin, T. K.,, Egund, L.,, Bartosch, P.,, Lund University., Ekstubbe, H.,, Malmgren, Linnea,   +5 more
core   +1 more source

Effect of various exercises on frailty among older adults with subjective cognitive concerns: a randomised controlled trial [PDF]

, 2020
Background: Physical exercise has been linked to reduced frailty, but there is insufficient evidence of beneficial effects in community-dwelling older adults with subjective cognitive concerns.
Huang Chi Hsien, Hayashi, Takahiro, Kuzuya, Masafumi, Shimada, Hiroyuki, Makino, Taeko, Kitada, Tomoharu, Uemura, Kazuki, Inoue, Aiko, Umegaki, Hiroyuki   +8 more
core   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source