Results 51 to 60 of about 269,169 (284)

Androstenedione and Follicle-Stimulating Hormone Concentration Predict the Progression of Frailty Syndrome at One Year Follow-Up in Patients with Localized Breast Cancer Treated with Aromatase Inhibitors

Biomedicines, 2022
Background: The standard treatment in postmenopausal women with estrogen- and progesterone-positive localized breast cancer consists of aromatase inhibitors (AROi).
Javier García-Sánchez, Mayra Alejandra Mafla-España, María Dolores Torregrosa, Omar Cauli   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Baseline Frailty Measured by the Risk Analysis Index and 30-Day Mortality After Surgery for Spinal Malignancy: Analysis of a Prospective Registry (2011–2020) [PDF]

Neurospine
Objective To evaluate the prognostic utility of baseline frailty, measured by the Risk Analysis Index (RAI), for prediction of postoperative mortality among patients with spinal malignancy (SM) undergoing resection.
Rachel Thommen, Christian A. Bowers, Aaron C. Segura, Joanna M. Roy, Meic H. Schmidt   +4 more
doaj   +1 more source

A Review of Frailty Syndrome and Its Physical, Cognitive and Emotional Domains in the Elderly [PDF]

, 2017
Peer reviewedPublisher ...
Khezrian, Mina, McNeil, Christopher J., Murray, Alison D., Myint, Phyo K.   +3 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Surgical menopause and frailty risk in older community dwelling women: the study of osteoporotic fractures [PDF]

, 2016
BACKGROUND: Low testosterone levels in older women have been shown to be associated with frailty. Whether older postmenopausal women with a history of bilateral oophorectomy before natural menopause resulting in lower testosterone levels (surgical ...
Huang, Grace
core   +1 more source

Types of dependence and time-dependent association between two lifetimes in single parameter copula models [PDF]

, 2006
Most publications on modeling insurance contracts on two lives, assuming dependence of the two lifetimes involved, focus on the time of inception of the contract.
Spreeuw, J.
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Industrial development under institutional frailty: the development of the Mexican textile industry in the nineteenth century [PDF]

, 1999
La Historia Económica en Latinoamérica. Edición a cargo de Pablo Martín Aceña, Adolfo Meisel, Carlos Newland.Editada en la Fundación Empresa PúblicaLa industria textil moderna apareció en México tempranamente y creció de forma continua a lo largo del ...
Alamán, Alamán, Atack, Batou, Bazant, Bernecker, Butterfiel, Cerotti, Clark, Clark, Clarke, Coatsworth, Coatsworth, Coatsworth, Coatsworth, Cosío Villegas, De Antuñano, Díaz Cayeros, Evans, Farnham, Fogel, García Cubas, Haber, Haber, Kane, Keremitsis, Maddison, Marichal, North, North, Plana, Potash, Pérez Hernández, Rosovsky, Schoonover, Takajusa, Thomson, Trujillo Bolio, Tyler, Walker, Wright, Zoriada Vázquez   +41 more
core   +3 more sources

Randomization-Based Confidence Intervals for Cluster Randomized Trials [PDF]

, 2020
In a cluster randomized trial (CRT), groups of people are randomly assigned to different interventions. Existing parametric and semiparametric methods for CRTs rely on distributional assumptions or a large number of clusters to maintain nominal ...
Rabideau, Dustin J, Wang, Rui
core   +2 more sources