Results 51 to 60 of about 198,435 (213)

Androstenedione and Follicle-Stimulating Hormone Concentration Predict the Progression of Frailty Syndrome at One Year Follow-Up in Patients with Localized Breast Cancer Treated with Aromatase Inhibitors

Biomedicines, 2022
Background: The standard treatment in postmenopausal women with estrogen- and progesterone-positive localized breast cancer consists of aromatase inhibitors (AROi).
Javier García-Sánchez, Mayra Alejandra Mafla-España, María Dolores Torregrosa, Omar Cauli   +3 more
doaj   +1 more source

Relative sit-to-stand power cut-off points and their association with negatives outcomes in older adults

Scientific Reports, 2021
The purposes of this study were: (i) to evaluate the association of sit-to-stand (STS) power and body composition parameters [body mass index (BMI) and legs skeletal muscle index (SMI)] with age; (ii) to provide cut-off points for low relative STS power (
Ivan Baltasar-Fernandez, Julian Alcazar, Asier Mañas, Luis M. Alegre, Ana Alfaro-Acha, Leocadio Rodriguez-Mañas, Ignacio Ara, Francisco J. García-García, Jose Losa-Reyna   +8 more
doaj   +1 more source

Oxidative Stress and Cognitive Alterations Induced by Cancer Chemotherapy Drugs: A Scoping Review

Antioxidants, 2021
Cognitive impairment is one of the most deleterious effects of chemotherapy treatment in cancer patients, and this problem sometimes remains even after chemotherapy ends.
Omar Cauli
doaj   +1 more source

Evaluation of muscle quality and quantity for the assessment of sarcopenia using mid-thigh computed tomography: a cohort study

BMC Geriatrics, 2021
Background For the diagnosis of Sarcopenia, European Working Group on Sarcopenia in Older People (EWGSOP) revised the algorisms in 2019, where they added computed tomography (CT) as an assessment tool not only for quantity but also for quality in ...
Hiroki Oba, Yasumoto Matsui, Hidenori Arai, Tsuyoshi Watanabe, Hiroki Iida, Takafumi Mizuno, Satoshi Yamashita, Shinya Ishizuka, Yasuo Suzuki, Hideki Hiraiwa, Shiro Imagama   +10 more
doaj   +1 more source

Measuring Frailty among Older People : Further Evaluation of the Brody Frailty Index

, 2017
BACKGROUND AND OBJECTIVE: The study aimed to evaluate the predictive validity of the Brody self-report frailty index among older people. Design, setting and measurements: A longitudinal cohort study (2-years) conducted in Sweden, which included 1141 ...
Jakobsson, U., Jakobsson, U.,, Lund University., U. Jakobsson   +3 more
core   +1 more source

Gut frailty: the core of reversing frailty

Annals of Medicine
Imbalances in gut microbiota have been implicated in numerous age-related degenerative diseases and unhealthy aging. Frail individuals often exhibit severe malnutrition and gastrointestinal dysfunction. Recent studies have demonstrated a correlation between physical frailty, cognitive decline, gastrointestinal function, and intestinal microbiota ...
Yu Pan, Juan Yang, Yi Jiang, Zhu Qing Feng, Xue Yin Tang, Yan Yuan, Gui Ming Hu, Dong Li Luo, Yang Jiang, Jiang Chuan Dong   +9 more
openaire   +3 more sources

Frailty in ethnic minority women

, 2021
In majority populations in high- and middle-income countries, women live longer yet experience higher levels of frailty than men of the same age. It is unclear whether this ‘sex–frailty paradox’ is present in ethnic minority populations.
Weerasekera, S, Reid, N, Gordon, EH, Hubbard, RE, Shavini Weerasekera, Emily H Gordon, Ruth E Hubbard, Natasha Reid   +7 more
core   +1 more source

A Novel Bead-Based Immunoassay for the Measurement of Heat Shock Proteins 27 and 70

Pathogens, 2020
Heat shock proteins (HSPs) play an essential role in protecting proteins from denaturation and are implicated in diverse pathophysiological conditions like cardiovascular diseases, cancer, infections, and neurodegenerative diseases.
Rose Njemini, Katrijn Verhaeghen, Tony Mets, Ilse Weets, Ivan Bautmans   +4 more
doaj   +1 more source

Investigating the role of frailty in the expression of dementia

, 2020
Background: Frailty is related to neuropathological features of Alzheimer’s disease (AD) as well as cognitive decline and dementia. Objectives: 1) determine whether frailty moderates the relationship between neuropathology and dementia status in ...
Wallace, Lindsay M K
core  

Rapid increase in departmental scholarly activity independent of residents demonstrates reproducibility and success of intensive research initiative in neurosurgery department

World Neurosurgery: X
Background: Neurological surgery remains one of the most competitive specialties with a match rate of
Samantha Varela, Meic H. Schmidt, Christian A. Bowers   +2 more
doaj   +1 more source