Background: The standard treatment in postmenopausal women with estrogen- and progesterone-positive localized breast cancer consists of aromatase inhibitors (AROi).
Javier García-Sánchez +3 more
doaj +1 more source
Randomization-Based Confidence Intervals for Cluster Randomized Trials [PDF]
In a cluster randomized trial (CRT), groups of people are randomly assigned to different interventions. Existing parametric and semiparametric methods for CRTs rely on distributional assumptions or a large number of clusters to maintain nominal ...
Rabideau, Dustin J, Wang, Rui
core +2 more sources
Quality of life with conservative care compared with assisted peritoneal dialysis and haemodialysis [PDF]
Background. There is little information about quality of life (QoL) for patients with end-stage kidney disease (ESKD) choosing conservative kidney management (CKM).
Barendse +26 more
core +4 more sources
Baseline Frailty Measured by the Risk Analysis Index and 30-Day Mortality After Surgery for Spinal Malignancy: Analysis of a Prospective Registry (2011–2020) [PDF]
Objective To evaluate the prognostic utility of baseline frailty, measured by the Risk Analysis Index (RAI), for prediction of postoperative mortality among patients with spinal malignancy (SM) undergoing resection.
Rachel Thommen +4 more
doaj +1 more source
A single weekly Kt/Vurea target for peritoneal dialysis patients does not provide an equal dialysis dose for all [PDF]
Copyright © 2016 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.Dialysis adequacy is traditionally based on urea clearance, adjusted for total body volume (Kt/Vurea), and clinical guidelines recommend a Kt/Vurea ...
Davenport, Andrew +4 more
core +2 more sources
Background For the diagnosis of Sarcopenia, European Working Group on Sarcopenia in Older People (EWGSOP) revised the algorisms in 2019, where they added computed tomography (CT) as an assessment tool not only for quantity but also for quality in ...
Hiroki Oba +10 more
doaj +1 more source
Beta-blockers and physical frailty in patients with end-stage liver disease. [PDF]
AimTo investigate beta-blocker (BB) use in patients with cirrhosis and determine their effects on physical frailty and overall survival.MethodsAdult outpatients with cirrhosis listed for liver transplantation underwent testing of physical frailty using ...
Hayssen, Hilary +3 more
core
Implant Treatment in the Predoctoral Clinic: A Retrospective Database Study of 1091 Patients [PDF]
Purpose: This retrospective study was conducted at the Marquette University School of Dentistry to (1) characterize the implant patient population in a predoctoral clinic, (2) describe the implants inserted, and (3) provide information on implant ...
Bansal, Naveen K. +5 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Oxidative Stress and Cognitive Alterations Induced by Cancer Chemotherapy Drugs: A Scoping Review
Cognitive impairment is one of the most deleterious effects of chemotherapy treatment in cancer patients, and this problem sometimes remains even after chemotherapy ends.
Omar Cauli
doaj +1 more source

