Results 131 to 140 of about 22,515 (245)

Frailty in anesthesia. [PDF]

open access: yesCurr Opin Anaesthesiol
Klaschik S   +3 more
europepmc   +1 more source

Investigating the interplay between frailty and healthcare utilization in older adults [Elektronisk resurs]

open access: yes
Frailty, a syndrome characterized by physiological decline and below average resilience to stressors, often results in clinical complexity and poor quality of life. In this thesis, we examine how frailty has evolved over time in the older population, its
Tazzeo, CO,
core   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source

Caring for the frail: a qualitative study in an orthopaedic setting. [PDF]

open access: yesBMC Geriatr
Hammer A   +3 more
europepmc   +1 more source

Investigating the interplay between frailty and healthcare utilization in older adults

open access: yes
Frailty, a syndrome characterized by physiological decline and below average resilience to stressors, often results in clinical complexity and poor quality of life. In this thesis, we examine how frailty has evolved over time in the older population, its
Clare Tazzeo (18667807)
core   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

open access: yesBMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning   +10 more
wiley   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

open access: yesBMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li   +9 more
wiley   +1 more source

Rising Strong: Cultivating Resilience in Edible City Entrepreneurship. Insights Into the Landscape of Urban Food Initiatives

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT In response to growing global challenges, this study explores how social entrepreneurship within the Edible City movement contributes to building resilient, sustainable, and equitable urban food systems. Drawing on semistructured interviews with over 70 stakeholders across five cities—Berlin, Andernach, Oslo, Rotterdam, and Havana—we ...
Ina Säumel   +6 more
wiley   +1 more source

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