Results 181 to 190 of about 57,728 (258)

Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making

Epilepsia, EarlyView.
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe, František Bartoš, Eric‐Jan Wagenmakers, Kees P. J. Braun, Floor E. Jansen, Willem M. Otte   +5 more
wiley   +1 more source

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

Epilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie, Inge M. W. Verberk, Jans S. van Ool, Anneke J. J. Rampen, Rebecca Z. Rousset, Nicole I. Wolf, Dederieke A. M. Maes‐Festen, Clara D. M. van Karnebeek, Charlotte E. Teunissen, Erik Boot, Agnies M. van Eeghen   +10 more
wiley   +1 more source

Impact of Chronic Limb-Threatening Ischemia in Patients on Hemodialysis. [PDF]

J Atheroscler Thromb
Ohtake T, Kobayashi S.
europepmc   +1 more source

Reliability and Degradation Mechanisms of Photovoltaic Modules in Pakistan

Energy Science &Engineering, EarlyView.
Reliability of the PV module. ABSTRACT The number of photovoltaic (PV) installations has grown rapidly in the last 10 years in Pakistan due to the growing electricity demand, the availability of favourable solar resources, and the national renewable energy objectives.
Zafar Ullah Khan, Adnan Daud Khan, Muhammad Ahsan Amjed   +2 more
wiley   +1 more source

Development and Testing a Measure of Experienced Frailty for Community-Dwelling Older Adults: The Frailty Experiences Scale (FES). [PDF]

Sage Open Aging
Golbach RDJ, Hobbelen HJSM, Krijnen WP, Jager-Wittenaar H, Finnema E.   +4 more
europepmc   +1 more source

Deprivation and Accidental Dwelling Fires in the Greater Manchester Area Between 2013–2014 and 2023–2024

Fire and Materials, EarlyView.
ABSTRACT In this article, the relationship between the level of deprivation, measured by the Indices of Multiple Deprivation decile (IMD decile) determined by the UK Ministry of Housing, Communities and Local Government, and the number of different types of accidental dwelling fires (ADFs) in populations across the different IMD deciles is examined ...
M. Taylor, E. Dean, J. Fielding, R. Lyon, V. Kwasnica   +4 more
wiley   +1 more source

Frailty assessment and candidate optimization before cardiothoracic transplantation. [PDF]

JHLT Open
Premachandra A, Klapper J, Messika J, Gaillard M, Kloeckner M, Ghadimi K, Reffienna M, Ingle K, Magudia K, Bottiger B.   +9 more
europepmc   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

Flavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou, Yi Yue, Wenwen Qi, Wenqing Zhu, Xinran Liu, Rongcui Sui, Xuanchen Zhou   +6 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Vitamin D deficiency and disease conditions relevant to: Orthopaedic translation. [PDF]

J Orthop Translat
Ekanayake Mudiyanselage D, Ouyang CE, Jin RD, Velmurugan S, Jiang Y, Sun J, Ma D.   +6 more
europepmc   +1 more source