Luzhou‐Flavor Baijiu Alleviates Stress‐Related Depressive‐Like Changes by NMDAR‐NO‐sGC‐cGMP Pathway
Luzhou‐flavor baijiu (LFB) alleviates depressive‐like phenotypes in CRS‐induced mice and protects HT22 cells from corticosterone damage, with mechanisms linked to suppressing the NMDAR‐nNOS/iNOS‐NO‐sGC‐cGMP pathway. ABSTRACT Moderate alcohol consumption has been suggested to alleviate anxiety and depression; however, it remains unclear whether Luzhou ...
Li Xiong +10 more
wiley +1 more source
Survey of Spanish nephrologists' opinion on the applicability of Fried's geriatric frailty criteria in patients with end-stage renal disease. [PDF]
Pérez-Fernández M +6 more
europepmc +1 more source
ABSTRACT Background Post‐stroke gastroparesis (GP) is a debilitating complication that severely impairs quality of life. Although abdominal acupuncture is widely used, robust evidence regarding its efficacy, particularly concerning the critical parameter of the needling depth, is still lacking.
Xiangcheng Wei +8 more
wiley +1 more source
Study protocol for a multiarm, randomized controlled trial to determine the effectiveness of community-based frailty rehabilitation to improve physical function in older adults: The OPTIMAL Fitness Trial. [PDF]
Papaioannou A +26 more
europepmc +1 more source
ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley +1 more source
ABSTRACT Physical fitness is well‐known to be associated with health outcomes. This pilot study examined the impact of different measures of fitness on length of stay following colectomy. A case‐control study was designed to evaluate the effect of skeletal muscle mass, body fat, and frailty measures on post‐operative length of stay (LOS).
Annmarie Butare +2 more
wiley +1 more source
Frailty classification challenges in the emergency department: agreement and variability in clinical frailty scale scoring. [PDF]
Netland CK +5 more
europepmc +1 more source
Our analysis of 3636 participants from the nationally representative CHARLS cohort revealed that 8.7% of older adults with multimorbidities declined hospitalization despite medical necessity. This under‐utilization was associated with significant long‐term health deterioration, including reduced self‐rated health, impaired work capacity, and diminished
Yunlian Xue +3 more
wiley +1 more source
The Modified 5-Item Frailty Index as a Predictor of Postoperative Complications in Patients Undergoing Spinal Surgery. Performance Comparison at Different Levels of Surgical Complexity. [PDF]
Kido G +5 more
europepmc +1 more source

