Results 81 to 90 of about 57,728 (258)
Exercise rehabilitation for recovery from critical illness (Protocol) [PDF]
, 2010 Queen Margaret University, Edinburgh, UK. As part of an ongoing research education programme.This is the protocol for a review and there is no abstract.
Geneen, L +4 more
core +1 more source
Advanced Science, EarlyView.Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
Frailty In Patients Undergoing Vascular Surgery: A Narrative Review Of Current Evidence
Therapeutics and Clinical Risk Management, 2019 Nikoletta Rahel Czobor,1,2 Jean-Jacques Lehot,3,4 Eniko Holndonner-Kirst,1 Phillip J Tully,5 Janos Gal,6 Andrea Szekely6,7 1Medical Centre of Hungarian Defense Forces, Department of Anesthesiology and Intensive Care, Budapest, Hungary; 2Semmelweis ...
Czobor NR +5 more
doaj
Advanced Science, EarlyView.This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia +6 more
wiley +1 more source
International Journal of Integrated Care, 2019 Introduction: An increasing number of older people living at home with complex needs challenges health and social care systems. SUSTAIN or ‘Sustainable Tailored Integrated Care for Older People in Europe’ is a 4-year project which aims to support and ...
Julie MacInnes +2 more
doaj +1 more source
Trauma and acute care surgeons report prescribing less opioids over time. [PDF]
, 2019 IntroductionConfronted with the opioid epidemic, surgeons must play a larger role to reduce risk of opioid abuse while managing acute pain. Having a better understanding of the beliefs and practices of trauma and acute care surgeons regarding discharge ...
Anderson, Jamie E +2 more
core +2 more sources
TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration
Advanced Science, EarlyView.TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu +9 more
wiley +1 more source
Screening for frailty: older populations and older individuals [PDF]
, 2016 The concept of frailty as a health dimension in old age is recent and has its origin in the development of geriatric medicine. Initially an unformulated clinical intuition, it is now defined by a diminished physiological reserve of multiple organs that ...
Santos-Eggimann, Brigitte +1 more
core +2 more sources
Advanced Science, EarlyView.The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source
Childhood mortality in sub-Saharan Africa : cross-sectional insight into small-scale geographical inequalities from Census data [PDF]
, 2012 Objectives To estimate and quantify childhood mortality, its spatial correlates and the impact of potential correlates using recent census data from three sub-Saharan African countries (Rwanda, Senegal and Uganda), where evidence is lacking.
Clarke, Aileen +2 more
core +1 more source