Results 61 to 70 of about 58,166 (260)

Multi‐Responsive Dendrimer‐Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy

Advanced Functional Materials, EarlyView.
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu, Mengsi Zhan, Haoyu Huang, Jianhong Wang, Cheng Ni, Xiaojun Zhou, Hannah Küttner, Cong Song, Xiangyang Shi, Andrij Pich   +9 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Bridging aortic valve surgery to 21st century. what can a surgeon do [PDF]

, 2019
Aortic valve stenosis is the most clinically relevant valvular heart disease in the elderlies. Surgical aortic valve replacement (SAVR) represented, for decades, the standard of care for the treatment of severe aortic stenosis.
Barretta, Antonio, Biondi-Zoccai, Giuseppe, D��Abramo, Mizar, Ferrante, Luisa, Frati, Giacomo, Greco, Ernesto, Guerrera, Manuel, Iaccarino, Alessandra, Marullo, Antonino, Miraldi, Fabio, Peruzzi, Mariangela, Proietti, Piero, Saade, Wael, Sciarretta, Sebastiano   +13 more
core   +1 more source

Fabric‐Based Wearable Robotic Exoskeleton Gloves: Advancements and Challenges

Advanced Materials Technologies, EarlyView.
This review highlights interdisciplinary technological advances in fabric‐based robotic gloves, focusing on progress in design, fabrication, actuation, sensing, control, and power and energy requirements. It also addresses performance testing and validation, including biomechanical, strength, functional, user experience, and durability assessments, to ...
Ayse Feyza Yilmaz, Gökhan Ince, Ozgur Atalay   +2 more
wiley   +1 more source

Profiles of physical frailty, social frailty, and cognitive impairment among older adults in rural areas of China: a latent profile analysis

Frontiers in Public Health
BackgroundAs China rapidly ages, it has now become a deeply aging society with the largest number of older individuals in the world. The issue is particularly severe in rural areas.
Qian Dong, Xiaolong Bu, Ting Wang, Man Liu, Feng Zhong, Cuiping Liu   +5 more
doaj   +1 more source

Older patients’ perspectives on factors contributing to frequent visits to the emergency department: a qualitative interview study

BMC Public Health, 2021
Background Older patients are at high risk of unplanned revisits to the emergency department (ED) because of their medical complexity. To reduce the number of ED visits, we need more knowledge about the patient-level, environmental, and healthcare ...
Daisy Kolk, Anton F. Kruiswijk, Janet L. MacNeil-Vroomen, Milan L. Ridderikhof, Bianca M. Buurman   +4 more
doaj   +1 more source

Exercise for falls prevention in community-dwelling older adults: Trial and participant characteristics, interventions and bias in clinical trials from a systematic review [PDF]

, 2019
IntroductionThere is strong evidence that exercise prevents falls in community-dwelling older people. This review summarises trial and participant characteristics, intervention contents and study quality of 108 randomised trials evaluating exercise ...
Fairhall, Nicola, Michaleff, Zoe A., Ng, Christopher A.C.M., Sherrington, Catherine, Tiedemann, Anne, Wallbank, Geraldine   +5 more
core   +1 more source

Radiative Cooling by Green(er) Solvents‐Upcycled Polyvinyl Chloride From Drug Blisters Waste

Advanced Optical Materials, EarlyView.
This study explores upcycling poly(vinyl chloride) (PVC) from used pharmaceutical blisters into sustainable radiative cooling materials. Using solvent separation and membrane fabrication, PVC was converted into white membranes paired with aluminum foil.
Andrea Lanfranchi, Paola Lova, Davide Comoretto   +2 more
wiley   +1 more source

NutriLive: An Integrated Nutritional Approach as a Sustainable Tool to Prevent Malnutrition in Older People and Promote Active and Healthy Ageing—The EIP-AHA Nutrition Action Group

Advances in Public Health, 2016
The present document describes a nutritional approach that is nested in the European Innovation Partnership for Active and Healthy Aging (EIP-AHA) and aims to provide the first common European program translating an integrated approach to nutritional ...
Maddalena Illario, Angela Serena Maione, Maria Rosaria Rusciano, Edwig Goossens, Amelia Rauter, Nidia Braz, Harriet Jager-Wittenaar, Carolina Di Somma, Catherine Crola, Maria Soprano, Laura Vuolo, Pietro Campiglia, Guido Iaccarino, Helen Griffiths, Tobias Hartman, Donatella Tramontano, Annamaria Colao, Regina Roller-Wirnsberger   +17 more
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source