Results 51 to 60 of about 25,104 (242)

Assessment of frailty in old people with multimorbidity

, 2023
Background: As the population grows older, understanding and management of multimorbidity and frailty will become increasingly important. There is no consensus on how to define or measure frailty and awareness of frailty is limited in many healthcare ...
Amelie Lindh Mazya (18652666)
core   +1 more source

Low patient activation levels in frail older adults: a cross-sectional study

BMC Geriatrics, 2018
Background Frail older adults are increasingly expected to self-manage their health and healthcare. We assessed the extent to which this group is able to take up this responsibility by measuring their level of activation as patients (i.e. their knowledge,
Anouk Overbeek, Judith A. C. Rietjens, Lea J. Jabbarian, Johan Severijnen, Siebe J. Swart, Agnes van der Heide, Ida J. Korfage   +6 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Characteristics of anesthetic management in elderly patients with frailty syndrome

Zaporožskij Medicinskij Žurnal
The increase in the proportion of elderly people has led to a proportional increase in geriatric patients undergoing surgical treatment. Elderly patients often develop geriatric syndromes, one of which is the frailty syndrome. Aim.
O. A. Halushko, L. M. Zenkina
doaj   +1 more source

Time to early initiation of postnatal care service utilization and its predictors among women who gave births in the last 2 years in Ethiopia: a shared frailty model

Archives of Public Health, 2021
Background Most maternal and infant deaths occurred within the first month after birth. Nearly half of the maternal deaths and more than a million newborn deaths occurred within the first day of life but these were preventable through early initiation of
Ayal Debie, Getayeneh Antehunegn Tesema
doaj   +1 more source

Self-Care, Treatment Adherence, and Frailty in Older Adults With Hypertension: A Descriptive Correlational Study

Background: – Hypertension is a prevalent condition among older adults and a major contributor to morbidity, mortality, and frailty in this population.
GÖK METİN, ZEHRA, Cili, Kubra
core   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Profiles of physical frailty, social frailty, and cognitive impairment among older adults in rural areas of China: a latent profile analysis

Frontiers in Public Health
BackgroundAs China rapidly ages, it has now become a deeply aging society with the largest number of older individuals in the world. The issue is particularly severe in rural areas.
Qian Dong, Xiaolong Bu, Ting Wang, Man Liu, Feng Zhong, Cuiping Liu   +5 more
doaj   +1 more source

Supplementary Material for: Methods of Assessing Frailty in the Critically Ill: A Systematic Review of the Current Literature

, 2022
Introduction: As new treatments have become established, more frail pre-ICU patients are being admitted to intensive care units (ICUs); this is creating new challenges to provide adequate care and to ensure that resources are allocated in an ethical and ...
Donatsch C. (12293345), Waskowski J. (12293339), Schefold J.C. (7338380), Pfortmueller C.A. (12293348), Bertschi D. (12293336), Schilling M. (12293342)   +5 more
core   +1 more source