Results 41 to 50 of about 246,066 (298)
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Using counterfactuals to display facts – the case of satirical humor
ExELL (Explorations in English Language and Linguistics), 2016 Satire has not been given the humorologists’ attention to an extent that would do justice to the amount of humor satire actually holds. Therefore, the intention of this paper is to shed light on satire as humorous discourse, with an emphasis on ...
Maslo Adi
doaj +1 more source
Frontiers in Communication, 2020 In Canada, the provincial government of British Columbia has been keen on building an export-oriented liquefied natural gas (LNG) industry since 2011. This paper examines media coverage of the Pacific NorthWest LNG project (PNW), which was considered as ...
Sibo Chen
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Dynamic and Function of Framing in Journalism: A Model Based on 9/11 News Reports
SAGE OpenMany studies treat news framing as a static phenomenon and fail to capture the framing process during breaking news events. This study explores the dynamic nature of news framing through an analysis of The New York Times’ continuous reporting on the ...
Jianxin Yang, Pingyan Li
doaj +1 more source
Motivating household food waste reduction: Harnessing the power of message context and framing
Food Frontiers, 2023 Household food waste is a major contributor to the total food waste from all sectors globally. Food waste undermines sustainability and reduces the resilience of food systems.
Toritseju Begho, Ningxin Zhao
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Through Smoke to Policy: Framing the EU Forest Fire Policy Landscape
LandThe global community is grappling with a significant increase in forest fires’ frequency, size, and intensity, presenting a profound challenge. To complement existing framing literature on forest fires, this paper examines collective frames applied to ...
Filip Aggestam
doaj +1 more source
Single-Frame, Multiple-Frame and Framing Motifs in Genes [PDF]
Life, 2019 We study the distribution of new classes of motifs in genes, a research field that has not been investigated to date. A single-frame motif SF has no trinucleotide in reading frame (frame 0) that occurs in a shifted frame (frame 1 or 2), e.g., the dicodon AAACAA is S F as the trinucleotides AAA and CAA do not occur in a shifted frame.
openaire +4 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source