Results 41 to 50 of about 84,659 (260)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Batak Cultural Change in Ngeri-ngeri Sedap Movie: Robert N Entman Framing Analysis
This research aims to reveal the changes in Batak culture in the movie Ngeri-ngeri Sedap. Ngeri-ngeri Sedap is a family-drama film with a Batak ethnic background, conveying the unrest of overseas children who are bound by customs and culture.
Ega Damayanti +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
KONSTRUKSI IDEOLOGI GENDER PADA MAJALAH WANITA (ANALISIS WACANA KRITIS MAJALAH UMMI)
UMMI’s magazine is one of Islamic magazine which is segmented for women and has positioned their self as da’wa media. The problems of this research are how UMMI construct the gender rules to their readers and how that rules are presented in this media ...
Ummy Hanifah
doaj +3 more sources
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Framing the Iraqi Refugee Crisis
Using headlines in digital media may strongly affect readers’ socio-political cognition (Abdel-Raheem & Alkhammash, 2022). That is, departing from Van Dijk’s claim (1988), constructing headlines in media is not always viewed as a syntax issue but rather
Ahmed Abed, Lorena Bort Mir
doaj +1 more source
The News Coverage of Indonesia Media toward AEC
The paper aims to elaborate the analysis of news coverage of Indonesia media toward ASEAN Economic Community (AEC) issue. Each media has its own framing of the news.
Heditia Syahputri Damanik
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Abstrak Konstruksi perempuan di media massa masih menjadi isu yang tidak ada usangnya. Tujuan penelitian ini ialah untuk mengidentifikasi, memahami bentuk-bentuk konstruksi perempuan serta mengetahui makna konstruksi perempuan di media ...
Dewi Ambarwati, Suranto Aw
doaj +1 more source

