Results 41 to 50 of about 74,598 (259)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

KONSTRUKSI IDEOLOGI GENDER PADA MAJALAH WANITA (ANALISIS WACANA KRITIS MAJALAH UMMI)

Komunika, 2015
UMMI’s magazine is one of Islamic magazine which is segmented for women and has positioned their self as da’wa media. The problems of this research are how UMMI construct the gender rules to their readers and how that rules are presented in this media ...
Ummy Hanifah
doaj   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Animation content in frame analysis [PDF]

Telfor Journal, 2016
Animation frame content is analyzed in this paper. The animation found in frame/video content is usually characterized by specific color distribution and texture. The existence of animation within a frame can be described by carefully selected features. We analyzed both fully and partially animated frames.
G. J. Zajić, M. D. Vesić, A. M. Gavrovska, I. S. Reljin   +3 more
openaire   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Framing the Iraqi Refugee Crisis

Cultura, Lenguaje y Representación
Using headlines in digital media may strongly affect readers’ socio-political cognition (Abdel-Raheem & Alkhammash, 2022). That is, departing from Van Dijk’s claim (1988), constructing headlines in media is not always viewed as a syntax issue but rather
Ahmed Abed, Lorena Bort Mir
doaj   +1 more source

The News Coverage of Indonesia Media toward AEC

Dinamika Global, 2016
The paper  aims  to  elaborate the  analysis of  news  coverage of  Indonesia media toward ASEAN Economic Community (AEC) issue. Each media has its own framing of the news.
Heditia Syahputri Damanik
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Konstruksi perempuan pada media daring alternatif Magdalene.co (analisis framing pada rubrik issues tentang relationship edisi bulan September-Desember 2019)

Lektur
Abstrak             Konstruksi perempuan di media massa masih menjadi isu yang tidak ada usangnya. Tujuan penelitian ini ialah untuk mengidentifikasi, memahami bentuk-bentuk konstruksi perempuan serta mengetahui makna konstruksi perempuan di media ...
Dewi Ambarwati, Suranto Aw
doaj   +1 more source